Chlorine in PDB 7lwf: Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320

The structure of Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320, PDB code: 7lwf was solved by D.A.Kuntz, G.G.Prive, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.96 / 1.22
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	30.473, 72.42, 55.592, 90, 106.31, 90
R / Rfree (%)	14.5 / 16.7

The binding sites of Chlorine atom in the Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320 (pdb code 7lwf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320, PDB code: 7lwf:

Chlorine binding site 1 out of 1 in the Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the BCL6 Btb Domain in Complex with Oicr-9320 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:16.3 occ:1.00 CL06 A:YNA201 0.0 16.3 1.0 C05 A:YNA201 1.7 16.0 1.0 C04 A:YNA201 2.7 17.0 1.0 HB3 A:ASN21 2.7 17.6 1.0 C07 A:YNA201 2.7 17.7 1.0 H071 A:YNA201 2.9 21.3 1.0 HD21 A:LEU25 2.9 18.5 1.0 N03 A:YNA201 2.9 16.4 1.0 HG A:LEU25 3.0 17.9 1.0 HD11 A:LEU25 3.2 19.1 1.0 CD2 A:LEU25 3.5 15.4 1.0 CG A:LEU25 3.6 14.9 1.0 CB A:ASN21 3.7 14.6 1.0 O A:ASN21 3.7 14.0 1.0 CD1 A:LEU25 3.8 15.9 1.0 HD23 A:LEU25 3.8 18.5 1.0 N08 A:YNA201 4.0 19.0 1.0 C10 A:YNA201 4.0 18.8 1.0 HD12 A:LEU25 4.2 19.1 1.0 C A:ASN21 4.2 13.8 1.0 CG A:ASN21 4.2 15.7 1.0 HB2 A:ASN21 4.2 17.6 1.0 C02 A:YNA201 4.3 16.7 1.0 HA A:ASN21 4.3 17.3 1.0 CA A:ASN21 4.3 14.4 1.0 HD22 A:LEU25 4.4 18.5 1.0 H111 A:YNA201 4.4 20.3 1.0 C09 A:YNA201 4.5 19.9 1.0 HD13 A:LEU25 4.6 19.1 1.0 HD22 A:ASN21 4.6 19.8 1.0 ND2 A:ASN21 4.7 16.5 1.0 OD1 A:ASN21 4.8 17.2 1.0 H101 A:YNA201 4.8 22.6 1.0 H A:LEU25 4.8 16.2 0.5 H A:LEU25 4.8 16.2 0.6 HB2 A:ARG24 4.8 17.1 0.6 HB2 A:ARG24 4.9 21.2 0.5 C11 A:YNA201 4.9 16.9 1.0

A.Mamai, M.Isaac. Discovery of OICR12694: A Novel, Potent, Selective and Orally Bioavailable BCL6 Btb Inhibitor To Be Published.