Chlorine in PDB 7lz2: Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine

The structure of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine, PDB code: 7lz2 was solved by S.P.Gangwar, M.N.Green, A.I.Sobolevsky, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	84.96 / 1.50
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	74.581, 74.581, 508.887, 90, 90, 120
R / Rfree (%)	18.5 / 20.9

The structure of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine (pdb code 7lz2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine, PDB code: 7lz2:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl302 b:59.0 occ:1.00 N B:GLY202 3.5 25.4 1.0 CA B:GLY202 4.2 23.7 1.0 CA B:VAL201 4.4 22.6 1.0 C B:VAL201 4.4 23.0 1.0 O B:GLY202 5.0 27.4 1.0

Chlorine binding site 2 out of 4 in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl302 b:63.0 occ:1.00 O C:ALA178 2.8 27.8 1.0 O C:ALA116 3.3 84.5 1.0 C C:ALA178 3.7 23.3 1.0 CD C:PRO112 3.7 32.4 1.0 CA C:ALA178 3.9 23.9 1.0 C C:ALA116 3.9 92.6 1.0 CG1 C:ILE119 3.9 41.8 1.0 O C:HOH440 4.0 26.3 1.0 CA C:ALA116 4.0 98.0 1.0 CB C:ALA178 4.2 25.6 1.0 O C:GLU115 4.2 86.7 1.0 CB C:ALA111 4.3 27.3 1.0 CG C:PRO112 4.4 36.1 1.0 CB C:ILE119 4.6 43.3 1.0 N C:PRO112 4.9 31.0 1.0 CB C:ALA116 4.9 94.1 1.0 N C:ALA116 4.9 98.4 1.0 N C:ALA179 5.0 22.8 1.0 C C:GLU115 5.0 92.1 1.0

Chlorine binding site 3 out of 4 in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl303 b:69.3 occ:1.00 NZ C:LYS7 3.6 50.0 1.0 CE C:LYS7 3.7 39.7 1.0 CD C:LYS7 4.0 37.0 1.0

Chlorine binding site 4 out of 4 in the Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Glutamate Receptor-Like Channel GLR3.4 Ligand-Binding Domain in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl304 b:63.2 occ:1.00 NZ C:LYS239 3.6 40.2 1.0 CE C:LYS239 4.1 35.0 1.0

M.N.Green, S.P.Gangwar, E.Michard, A.A.Simon, M.T.Portes, J.Barbosa-Caro, M.M.Wudick, M.A.Lizzio, O.Klykov, M.V.Yelshanskaya, J.A.Feijo, A.I.Sobolevsky. Structure of the Arabidopsis Thaliana Glutamate Receptor-Like Channel GLR3.4. Mol.Cell 2021.
ISSN: ISSN 1097-2765
PubMed: 34161757
DOI: 10.1016/J.MOLCEL.2021.05.025