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Chlorine in PDB 7ms7: Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine
Enzymatic activity of Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine
All present enzymatic activity of Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine:
3.4.19.12;
3.4.19.12;
Protein crystallography data
The structure of Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine, PDB code: 7ms7
was solved by
M.K.Mann,
C.A.Zepeda-Velazquez,
H.G.Alvarez,
A.Dong,
T.Kiyota,
A.Aman,
C.H.Arrowsmith,
R.Al-Awar,
R.J.Harding,
M.Schapira,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.42 / 1.45 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 61.556, 84.87, 59.542, 90, 98.86, 90 |
| R / Rfree (%) | 16.9 / 18.1 |
Other elements in 7ms7:
The structure of Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine also contains other interesting chemical elements:
| Zinc | (Zn) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine
(pdb code 7ms7). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine, PDB code: 7ms7:
In total only one binding site of Chlorine was determined in the Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine, PDB code: 7ms7:
Chlorine binding site 1 out of 1 in 7ms7
Go back to
Chlorine Binding Sites List in 7ms7
Chlorine binding site 1 out
of 1 in the Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Structure of USP5 Zinc-Finger Ubiquitin Binding Domain Co-Crystallized with (5-((4-(4-Chlorophenyl)Piperidin-1-Yl)Sulfonyl)Picolinoyl) Glycine within 5.0Å range:
|
Reference:
M.K.Mann,
C.A.Zepeda-Velazquez,
H.G.Alvarez,
A.Dong,
T.Kiyota,
A.Aman,
C.H.Arrowsmith,
R.Al-Awar,
R.J.Harding,
M.Schapira.
Structure Activity Relationship of Allosteric Inhibitors of USP5 To Be Published.
Page generated: Sun Jul 13 04:13:47 2025
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