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Chlorine in PDB 7n9g: Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and ImatinibEnzymatic activity of Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib
All present enzymatic activity of Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib:
2.7.10.2; Protein crystallography data
The structure of Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib, PDB code: 7n9g
was solved by
D.J.Miller,
T.Xie,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib
(pdb code 7n9g). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib, PDB code: 7n9g: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 7n9gGo back to Chlorine Binding Sites List in 7n9g
Chlorine binding site 1 out
of 3 in the Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 7n9gGo back to Chlorine Binding Sites List in 7n9g
Chlorine binding site 2 out
of 3 in the Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 7n9gGo back to Chlorine Binding Sites List in 7n9g
Chlorine binding site 3 out
of 3 in the Crystal Structure of the Abl 1B Kinase Domain in Complex with Dasatinib and Imatinib
Mono view Stereo pair view
Reference:
T.Xie,
T.Saleh,
P.Rossi,
D.Miller,
C.G.Kalodimos.
Imatinib Can Act As An Allosteric Activator of Abl Kinase. J.Mol.Biol. V. 434 67349 2022.
Page generated: Tue Apr 4 20:52:18 2023
ISSN: ESSN 1089-8638 PubMed: 34774565 DOI: 10.1016/J.JMB.2021.167349 |
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