Chlorine in PDB 7nd1: First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain

All present enzymatic activity of First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain:
2.3.2.27;

The structure of First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain also contains other interesting chemical elements:

Zinc

(Zn)

80 atoms

The binding sites of Chlorine atom in the First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain (pdb code 7nd1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain, PDB code: 7nd1:

Chlorine binding site 1 out of 1 in the First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of First-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl203 b:1.6 occ:1.00 CL1 A:U9E203 0.0 1.6 1.0 C4 A:U9E203 1.7 0.9 1.0 C5 A:U9E203 2.7 1.2 1.0 C3 A:U9E203 2.7 0.7 1.0 H10 A:U9E203 2.8 1.7 1.0 C2 A:U9E203 2.9 0.6 1.0 H5 A:U9E203 3.0 1.3 1.0 H16 A:U9E203 3.2 1.7 1.0 C1 A:U9E203 3.3 0.4 1.0 HG12 A:ILE77 3.5 0.6 1.0 C20 A:U9E203 3.6 1.0 1.0 C9 A:U9E203 3.7 1.2 1.0 HZ1 A:LYS97 3.7 0.8 1.0 HD13 A:ILE77 4.0 0.7 1.0 C8 A:U9E203 4.0 1.4 1.0 C6 A:U9E203 4.0 1.4 1.0 H8 A:U9E203 4.1 2.2 1.0 HD11 A:ILE77 4.1 0.7 1.0 HG23 A:ILE77 4.1 0.5 1.0 C11 A:U9E203 4.2 0.6 1.0 C10 A:U9E203 4.2 1.7 1.0 HE3 A:LYS97 4.2 0.6 1.0 C14 A:U9E203 4.3 1.6 1.0 HE2 A:LYS97 4.3 0.6 1.0 C21 A:U9E203 4.3 1.8 1.0 CD1 A:ILE77 4.3 0.7 1.0 CG1 A:ILE77 4.3 0.6 1.0 N1 A:U9E203 4.4 1.3 1.0 O1 A:U9E203 4.4 2.3 1.0 NZ A:LYS97 4.5 0.8 1.0 H7 A:U9E203 4.5 2.3 1.0 C7 A:U9E203 4.5 1.6 1.0 H6 A:U9E203 4.5 1.3 1.0 CE A:LYS97 4.6 0.6 1.0 HG21 A:ILE77 4.7 0.5 1.0 CG2 A:ILE77 4.8 0.5 1.0 H11 A:U9E203 4.9 1.7 1.0 H13 A:U9E203 4.9 1.9 1.0 HG13 A:ILE77 5.0 0.6 1.0 HZ2 A:LYS97 5.0 0.8 1.0 O2 A:U9E203 5.0 2.3 1.0

T.Cierpicki, G.Lung, L.Jaremko. Titlefirst-in-Class Small Molecule Inhibitors of Polycomb Repressive Complex 1 (PRC1) Ring Domain To Be Published.