Chlorine in PDB 7o28: Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009)

All present enzymatic activity of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009):
2.1.1.348;

The structure of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009), PDB code: 7o28 was solved by R.K.Bedi, A.Dolbois, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.40 / 2.47
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	63.871, 63.871, 224.515, 90, 90, 120
R / Rfree (%)	20.5 / 25.4

The binding sites of Chlorine atom in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009) (pdb code 7o28). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009), PDB code: 7o28:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:85.8 occ:1.00 CL1 A:UZB601 0.0 85.8 1.0 C29 A:UZB601 1.8 73.4 1.0 N31 A:UZB601 2.8 70.7 1.0 N28 A:UZB601 2.8 72.2 1.0 C A:LEU547 3.2 66.2 1.0 O A:LEU547 3.2 67.0 1.0 N A:GLY548 3.3 72.3 1.0 CA A:GLY548 3.4 73.9 1.0 CB A:LEU547 3.7 58.6 1.0 O A:CYS376 3.8 77.6 1.0 N A:ILE378 3.9 73.9 1.0 C A:GLY548 4.0 77.2 1.0 CB A:ILE378 4.0 71.2 1.0 N A:PHE534 4.0 63.9 1.0 CA A:LEU547 4.1 63.5 1.0 C22 A:UZB601 4.1 68.6 1.0 C27 A:UZB601 4.2 71.7 1.0 N A:ASN549 4.3 77.2 1.0 CG2 A:ILE378 4.3 68.9 1.0 CA A:PHE534 4.4 63.7 1.0 SG A:CYS376 4.4 93.0 1.0 CA A:ILE378 4.4 78.2 1.0 C A:CYS376 4.6 75.0 1.0 CD1 A:PHE534 4.6 66.3 1.0 O A:GLY548 4.7 72.8 1.0 C23 A:UZB601 4.7 70.9 1.0 C A:ASP377 4.7 74.4 1.0 CA A:ASP377 4.9 68.6 1.0 CE1 A:PHE534 5.0 62.6 1.0

R.K.Bedi, A.Dolbois, A.Caflisch. Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 19 (ADO_AE_009) To Be Published.