Chlorine in PDB 7onm: Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase)

Enzymatic activity of Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase)

All present enzymatic activity of Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase):
4.2.1.1; 4.2.1.69;

Protein crystallography data

The structure of Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase), PDB code: 7onm was solved by A.Stein, C.Dongping, Y.Cotelle, J.G.Rebelein, T.R.Ward, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	37.51 / 1.77
*Space group*	P 2₁ 2₁ 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	42.172, 73.959, 74.959, 90, 90, 90
*R / R_free (%)*	17.8 / 22.3

Other elements in 7onm:

The structure of Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase) also contains other interesting chemical elements:

Zinc	(Zn)	1 atom
Iridium	(Ir)	1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase) (pdb code 7onm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase), PDB code: 7onm:

Chlorine binding site 1 out of 1 in 7onm

Go back to

Chlorine Binding Sites List in 7onm

Chlorine binding site 1 out of 1 in the Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase)

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Carbonic Anhydrase II Mutant (N67G-E69R-I91C) Dually Binding An Ircp* Complex to Generate An Artificial Transfer Hydrogenase (Athase) within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl302 b:28.3 occ:1.00	CL1	A:VKZ302	0.0	28.3	1.0
	IR1	A:VKZ302	2.4	14.7	1.0
	N1	A:VKZ302	2.8	15.4	1.0
	N2	A:VKZ302	3.1	15.7	1.0
	O1	A:EDO303	3.1	32.5	1.0
	C5	A:VKZ302	3.2	13.8	1.0
	C6	A:VKZ302	3.3	14.6	1.0
	C17	A:VKZ302	3.3	16.4	1.0
	NH2	A:ARG69	3.5	42.5	1.0
	C18	A:VKZ302	3.5	16.1	1.0
	C1	A:VKZ302	3.5	13.5	1.0
	C1	A:EDO303	3.5	31.6	1.0
	C16	A:VKZ302	3.7	16.4	1.0
	NH1	A:ARG69	3.8	40.9	1.0
	C13	A:VKZ302	3.9	16.7	1.0
	C23	A:VKZ302	4.0	14.1	1.0
	CZ	A:ARG69	4.1	39.3	1.0
	C19	A:VKZ302	4.1	16.7	1.0
	O3	A:VKZ302	4.3	14.9	1.0
	C4	A:VKZ302	4.3	13.0	1.0
	C15	A:VKZ302	4.4	16.5	1.0
	C2	A:VKZ302	4.4	12.8	1.0
	C14	A:VKZ302	4.5	16.1	1.0
	O2	A:EDO304	4.5	34.6	1.0
	C22	A:VKZ302	4.6	15.7	1.0
	C3	A:VKZ302	4.8	13.2	1.0
	C2	A:EDO303	4.8	31.1	1.0

Reference:

A.Stein, D.Chen, N.V.Igareta, Y.Cotelle, J.G.Rebelein, T.R.Ward. A Dual Anchoring Strategy For the Directed Evolution of Improved Artificial Transfer Hydrogenases Based on Carbonic Anhydrase. Acs Cent.Sci. V. 7 1874 2021.
ISSN: ESSN 2374-7951
PubMed: 34849402
DOI: 10.1021/ACSCENTSCI.1C00825

Page generated: Sun Jul 13 05:17:46 2025

Last articles

Cl in 8BUC
Cl in 8BSU
Cl in 8BU2
Cl in 8BU1
Cl in 8BU4
Cl in 8BU0
Cl in 8BTI
Cl in 8BTE
Cl in 8BTC
Cl in 8BST

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy