Chlorine in PDB 7oo4: Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye

All present enzymatic activity of Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye:
3.8.1.5;

The structure of Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye, PDB code: 7oo4 was solved by A.Stein, A.D.Liang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.05 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.319, 68.986, 86.02, 90, 90, 90
R / Rfree (%)	21 / 26.3

The binding sites of Chlorine atom in the Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye (pdb code 7oo4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye, PDB code: 7oo4:

Chlorine binding site 1 out of 1 in the Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:38.2 occ:1.00 NE1 A:TRP107 3.3 32.9 1.0 N A:PRO206 3.5 37.2 1.0 ND2 A:ASN41 3.5 46.4 1.0 CA A:PRO206 3.6 37.5 1.0 C20 A:VF2402 3.7 44.9 1.0 CB A:PHE205 3.7 41.1 1.0 CD A:PRO206 3.8 35.8 1.0 CD1 A:LEU209 3.8 37.3 1.0 CD1 A:TRP107 3.8 34.3 1.0 C A:PHE205 3.9 37.0 1.0 CB A:PRO206 4.0 35.2 1.0 CB A:ASN41 4.0 39.1 1.0 C19 A:VF2402 4.0 45.2 1.0 CZ A:PHE168 4.1 43.2 1.0 CG A:LEU209 4.1 37.6 1.0 O A:PHE205 4.3 30.5 1.0 CD2 A:LEU209 4.3 38.5 1.0 CG A:ASN41 4.3 40.2 1.0 CE2 A:PHE149 4.3 38.6 1.0 CG A:PRO206 4.4 33.1 1.0 CE2 A:TRP107 4.4 33.4 1.0 CE2 A:PHE168 4.5 48.9 1.0 CA A:PHE205 4.5 39.1 1.0 CG A:PHE205 4.8 44.5 1.0 OD2 A:ASP106 5.0 30.5 1.0 CZ A:PHE149 5.0 37.9 1.0 C A:PRO206 5.0 41.9 1.0

C.Miro-Vinyals, A.Stein, S.Fischer, T.R.Ward, A.D.Liang. Halotag Engineering For Enhanced Fluorogenicity and Kinetics with A Styrylpyridine Dye To Be Published.