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Chlorine in PDB 7p5f: Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 InteractionProtein crystallography data
The structure of Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 Interaction, PDB code: 7p5f
was solved by
T.G.Davies,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 Interaction
(pdb code 7p5f). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 Interaction, PDB code: 7p5f: Chlorine binding site 1 out of 1 in 7p5fGo back to Chlorine Binding Sites List in 7p5f
Chlorine binding site 1 out
of 1 in the Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 Interaction
Mono view Stereo pair view
Reference:
D.Norton,
W.G.Bonnette,
J.F.Callahan,
M.G.Carr,
C.M.Griffiths-Jones,
T.D.Heightman,
J.K.Kerns,
H.Nie,
S.J.Rich,
C.Richardson,
W.Rumsey,
Y.Sanchez,
M.L.Verdonk,
H.M.G.Willems,
W.E.Wixted,
L.Wolfe 3Rd,
A.J.Woolford,
Z.Wu,
T.G.Davies.
Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-Like Ech-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction. J.Med.Chem. 2021.
Page generated: Thu Nov 25 08:55:33 2021
ISSN: ISSN 0022-2623 PubMed: 34705450 DOI: 10.1021/ACS.JMEDCHEM.1C01351 |
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