Chlorine in PDB 7pdc: The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation

The structure of The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation, PDB code: 7pdc was solved by K.Zeth, E.Sancho-Vaello, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.19 / 1.83
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	53.1, 51.42, 26.22, 90, 106.36, 90
R / Rfree (%)	25.2 / 30.2

The binding sites of Chlorine atom in the The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation (pdb code 7pdc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation, PDB code: 7pdc:

Chlorine binding site 1 out of 1 in the The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of the Human Tetrameric Ll-37 Peptide in A Channel Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl101 b:62.5 occ:0.50 O B:HOH206 3.6 38.4 1.0 NH2 B:ARG23 3.9 36.0 1.0 CD B:ARG19 4.1 50.3 1.0 NE A:ARG23 4.3 63.0 1.0 CB B:ARG19 4.5 33.3 1.0 NH2 A:ARG23 4.5 43.5 1.0 CG B:ARG19 4.5 40.8 1.0 NE B:ARG23 4.8 28.9 1.0 CZ B:ARG23 4.8 41.4 1.0 NE B:ARG19 4.9 60.5 1.0 CZ A:ARG23 4.9 60.5 1.0

E.Sancho-Vaello, D.Gil-Carton, P.Francois, E.J.Bonetti, M.Kreir, K.R.Pothula, U.Kleinekathofer, K.Zeth. The Structure of the Antimicrobial Human Cathelicidin Ll-37 Shows Oligomerization and Channel Formation in the Presence of Membrane Mimics. Sci Rep V. 10 17356 2020.
ISSN: ESSN 2045-2322
PubMed: 33060695
DOI: 10.1038/S41598-020-74401-5