Chlorine in PDB 7qkb: Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376

The structure of Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376, PDB code: 7qkb was solved by P.Y.A.Reinke, S.Falke, J.Lieske, W.Ewert, J.Loboda, A.Rahmani Mashhour, M.Hauser, K.Karnicar, A.Usenik, N.Lindic, M.Lach, H.Boehler, T.Beck, R.Cox, H.N.Chapman, W.Hinrichs, D.Turk, S.Guenther, A.Meents, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.25 / 1.80
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	57.29, 62.45, 67.82, 105.31, 93.52, 115.93
R / Rfree (%)	16.9 / 20.3

The structure of Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376 also contains other interesting chemical elements:

Sodium

(Na)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376 (pdb code 7qkb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376, PDB code: 7qkb:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Cathepsin L in Complex with Covalently Bound GC376 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:77.1 occ:1.00 HH12 A:ARG206 2.5 80.3 1.0 NH1 A:ARG206 3.2 66.9 1.0 HH11 A:ARG206 3.5 80.3 1.0 HH22 A:ARG206 4.0 85.5 1.0 CZ A:ARG206 4.2 70.1 1.0 NH2 A:ARG206 4.5 71.2 1.0

P.Y.A.Reinke, S.Falke, J.Lieske, W.Ewert, J.Loboda, A.Rahmani Mashhour, M.Hauser, K.Karnicar, A.Usenik, N.Lindic, M.Lach, H.Boehler, T.Beck, R.Cox, H.N.Chapman, W.Hinrichs, D.Turk, S.Guenther, A.Meents. Sulfonated Calpeptin Is A Promising Drug Candidate Against Sars-Cov-2 Infections To Be Published.