Chlorine in PDB 7rbr: The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin

Enzymatic activity of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin

All present enzymatic activity of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin:
3.4.19.12;

Protein crystallography data

The structure of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin, PDB code: 7rbr was solved by J.Osipiuk, C.Tesar, M.Endres, B.T.Lanham, P.Wydorski, D.Fushman, L.Joachimiak, A.Joachimiak, Center For Structural Genomics Ofinfectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.14 / 1.88
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 148.046, 50.136, 71.927, 90, 111.84, 90
R / Rfree (%) 18.7 / 22.8

Other elements in 7rbr:

The structure of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin (pdb code 7rbr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin, PDB code: 7rbr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 7rbr

Go back to Chlorine Binding Sites List in 7rbr
Chlorine binding site 1 out of 2 in the The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl502

b:68.2
occ:1.00
 O A:HOH672 3.1 46.2 1.0
N A:PHE127 3.2 35.5 1.0
CB A:PHE127 3.8 34.8 1.0
CG A:GLN133 3.8 45.2 1.0
CD2 A:PHE127 3.9 34.6 1.0
CA A:GLN133 4.0 37.7 1.0
CA A:PHE127 4.0 34.5 1.0
CA A:LYS126 4.1 41.8 1.0
C A:LYS126 4.1 37.4 1.0
O A:LEU125 4.2 43.8 1.0
CB A:GLN133 4.2 42.7 1.0
CG A:PHE127 4.3 35.0 1.0
O A:PHE127 4.3 34.0 1.0
CD A:LYS126 4.4 57.5 1.0
OH A:TYR137 4.5 74.6 1.0
C A:PHE127 4.7 34.7 1.0
CZ A:TYR137 4.8 67.2 1.0
N A:GLN133 4.8 34.6 1.0
C A:LEU125 4.9 41.2 1.0
CD A:GLN133 4.9 50.0 1.0
O A:GLN133 4.9 37.6 1.0
N A:LYS126 4.9 38.5 1.0
CE2 A:PHE127 4.9 35.9 1.0
CD2 A:TYR136 5.0 40.1 1.0

Chlorine binding site 2 out of 2 in 7rbr

Go back to Chlorine Binding Sites List in 7rbr
Chlorine binding site 2 out of 2 in the The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl503

b:70.9
occ:1.00
 O A:ASN15 2.8 40.6 1.0
OE1 A:GLU67 2.9 48.7 1.0
N A:VAL11 3.0 42.4 1.0
OG1 A:THR10 3.2 37.9 1.0
OD1 A:ASP12 3.3 43.1 1.0
CG2 A:VAL11 3.4 46.6 1.0
CA A:THR10 3.5 38.7 1.0
NE2 A:HIS17 3.5 42.0 1.0
CG A:ASP12 3.7 44.1 1.0
C A:THR10 3.7 40.5 1.0
CD2 A:HIS17 3.8 42.0 1.0
CD A:GLU67 3.8 48.3 1.0
C A:ASN15 3.8 42.3 1.0
N A:ASP12 3.9 42.1 1.0
CB A:ASN15 3.9 48.0 1.0
CB A:THR10 4.0 37.5 1.0
OD2 A:ASP12 4.0 43.5 1.0
CA A:VAL11 4.0 42.9 1.0
CB A:VAL11 4.1 43.0 1.0
CA A:ASN15 4.2 44.9 1.0
CB A:GLU67 4.3 44.8 1.0
CD2 A:LEU64 4.3 53.0 1.0
C A:VAL11 4.4 42.9 1.0
CG1 A:VAL11 4.4 47.3 1.0
N A:ASN15 4.4 43.3 1.0
CG A:GLU67 4.6 49.0 1.0
OE2 A:GLU67 4.6 53.6 1.0
CB A:ASP12 4.6 43.2 1.0
N A:THR10 4.8 39.8 1.0
CE1 A:HIS17 4.8 43.2 1.0
CA A:ASP12 4.8 41.4 1.0
O A:THR9 4.9 38.4 1.0
O A:THR10 4.9 39.9 1.0
N A:LEU16 5.0 41.2 1.0

Reference:

J.Osipiuk, C.Tesar, M.Endres, B.T.Lanham, P.Wydorski, D.Fushman, L.Joachimiak, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). The Crystal Structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with A LYS48-Linked Di-Ubiquitin To Be Published.
Page generated: Tue Jul 30 03:33:19 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy