Chlorine in PDB 7rmd: Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1

The structure of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1, PDB code: 7rmd was solved by T.R.Stachowski, M.Fischer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.12 / 1.18
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.634, 44.74, 78.236, 90, 90, 90
R / Rfree (%)	15.3 / 17.4

The binding sites of Chlorine atom in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1 (pdb code 7rmd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1, PDB code: 7rmd:

Chlorine binding site 1 out of 1 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:15.5 occ:0.99 CL1 A:5Z0202 0.0 15.5 1.0 C10 A:5Z0202 1.7 12.2 1.0 C11 A:5Z0202 2.6 12.0 1.0 H9 A:5Z0202 2.7 14.4 1.0 C9 A:5Z0202 2.8 14.8 1.0 H8 A:5Z0202 2.9 17.7 1.0 HB3 A:ASP145 3.0 19.3 1.0 HB2 A:ASP145 3.5 19.3 1.0 CB A:ASP145 3.6 16.1 1.0 SD A:MET149 3.7 12.1 1.0 HZ2 A:TRP81 3.7 16.4 1.0 OD2 A:ASP145 3.8 19.2 1.0 C12 A:5Z0202 4.0 11.4 1.0 C8 A:5Z0202 4.0 15.7 1.0 CG A:ASP145 4.1 24.3 1.0 HE1 A:MET149 4.3 16.4 1.0 HH2 A:TRP81 4.5 17.2 1.0 CZ2 A:TRP81 4.5 13.6 1.0 C7 A:5Z0202 4.5 11.5 1.0 CE A:MET149 4.6 13.7 1.0 O A:HOH438 4.7 28.6 1.0 H10 A:5Z0202 4.7 13.6 1.0 H7 A:5Z0202 4.8 18.8 1.0 HE3 A:MET149 4.8 16.4 1.0 CH2 A:TRP81 4.9 14.3 1.0 O A:HOH437 4.9 26.7 1.0 C A:ASP145 4.9 13.1 1.0 CA A:ASP145 5.0 14.8 1.0 HA A:ILE146 5.0 15.0 1.0

T.R.Stachowski, M.Fischer. Crystal Structure of the First Bromodomain of Human BRD4 in Complex with SJ001011461-1 To Be Published.