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Chlorine in PDB 7ss8: Human P300 Complexed with A Proline-Based InhibitorEnzymatic activity of Human P300 Complexed with A Proline-Based Inhibitor
All present enzymatic activity of Human P300 Complexed with A Proline-Based Inhibitor:
2.3.1.48; Protein crystallography data
The structure of Human P300 Complexed with A Proline-Based Inhibitor, PDB code: 7ss8
was solved by
L.M.Shewchuk,
R.A.Reid,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7ss8:
The structure of Human P300 Complexed with A Proline-Based Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human P300 Complexed with A Proline-Based Inhibitor
(pdb code 7ss8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human P300 Complexed with A Proline-Based Inhibitor, PDB code: 7ss8: Chlorine binding site 1 out of 1 in 7ss8Go back to Chlorine Binding Sites List in 7ss8
Chlorine binding site 1 out
of 1 in the Human P300 Complexed with A Proline-Based Inhibitor
Mono view Stereo pair view
Reference:
X.Tian,
D.Suarez,
D.Thomson,
W.Li,
E.A.King,
L.Lafrance,
J.Boehm,
L.Barton,
C.Di Marco,
C.Martyr,
R.Thalji,
J.Medina,
S.Knight,
D.Heerding,
E.Gao,
E.Nartey,
T.Cecconie,
C.Nixon,
G.Zhang,
T.J.Berrodin,
C.Phelps,
A.Patel,
X.Bai,
K.Lind,
N.Prabhu,
J.Messer,
Z.Zhu,
L.Shewchuk,
R.Reid,
A.P.Graves,
C.Mchugh,
B.Mangatt.
Discovery of Proline-Based P300/Cbp Inhibitors Using Dna-Encoded Library Technology in Combination with High-Throughput Screening. J.Med.Chem. V. 65 14391 2022.
Page generated: Tue Apr 4 21:43:23 2023
ISSN: ISSN 0022-2623 PubMed: 36302181 DOI: 10.1021/ACS.JMEDCHEM.2C00670 |
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