|
Chlorine in PDB 7t0e: Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2BEnzymatic activity of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B
All present enzymatic activity of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B:
2.5.1.58; Protein crystallography data
The structure of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B, PDB code: 7t0e
was solved by
Y.Wang,
Y.Shi,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7t0e:
The structure of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B
(pdb code 7t0e). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B, PDB code: 7t0e: Chlorine binding site 1 out of 1 in 7t0eGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpp and Inhibitor 2B
![]() Mono view ![]() Stereo pair view
Reference:
Y.Wang,
F.Xu,
C.B.Nichols,
Y.Shi,
H.W.Hellinga,
J.A.Alspaugh,
M.D.Distefano,
L.S.Beese.
Structure-Guided Discovery of Potent Antifungals That Prevent Ras Signaling By Inhibiting Protein Farnesyltransferase. J.Med.Chem. V. 65 13753 2022.
Page generated: Tue Apr 4 21:44:30 2023
ISSN: ISSN 0022-2623 PubMed: 36218371 DOI: 10.1021/ACS.JMEDCHEM.2C00902 |
Last articlesCl in 6COGCl in 6CST Cl in 6CTW Cl in 6CTZ Cl in 6CTT Cl in 6CSP Cl in 6CU9 Cl in 6CTX Cl in 6CTU Cl in 6CTP |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |