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Atomistry » Chlorine » PDB 7thh-7tp5 » 7tle | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7thh-7tp5 » 7tle » |
Chlorine in PDB 7tle: Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S)Enzymatic activity of Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S)
All present enzymatic activity of Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S):
3.6.5.2; Protein crystallography data
The structure of Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S), PDB code: 7tle
was solved by
Z.Ziyang,
K.Z.Guiley,
K.M.Shokat,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tle:
The structure of Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S)
(pdb code 7tle). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S), PDB code: 7tle: Chlorine binding site 1 out of 1 in 7tleGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Small Molecule Beta-Lactone 1 Covalently Bound to K-Ras(G12S)
![]() Mono view ![]() Stereo pair view
Reference:
Z.Zhang,
K.Z.Guiley,
K.M.Shokat.
Chemical Acylation of An Acquired Serine Suppresses Oncogenic Signaling of K-Ras(G12S). Nat.Chem.Biol. V. 18 1177 2022.
Page generated: Sun Jul 13 07:29:47 2025
ISSN: ESSN 1552-4469 PubMed: 35864332 DOI: 10.1038/S41589-022-01065-9 |
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