Chlorine in PDB 7vc2: Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21

The structure of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21, PDB code: 7vc2 was solved by Y.Manickam, N.Malhotra, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.42 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	77.1, 81.62, 104.88, 90, 102.68, 90
R / Rfree (%)	17.7 / 21.8

The structure of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21 also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Chlorine atom in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21 (pdb code 7vc2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21, PDB code: 7vc2:

Chlorine binding site 1 out of 1 in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L96 and L-Proline in Space Group P21 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl910 b:85.4 occ:1.00 OH B:TYR830 3.4 73.2 1.0 CD1 B:LEU480 3.9 50.2 1.0 CD2 B:TYR346 4.2 40.7 1.0 CE2 B:PHE342 4.2 48.3 1.0 CG B:TYR346 4.3 44.9 1.0 CB B:TYR346 4.4 40.3 1.0 CA B:SER343 4.4 49.8 1.0 CZ B:TYR830 4.5 63.2 1.0 CG2 B:THR477 4.5 53.8 1.0 CD2 B:PHE342 4.5 43.5 1.0 CB B:SER343 4.6 51.4 1.0 CE2 B:TYR830 4.6 59.3 1.0 SD B:MET601 4.7 43.5 1.0 CE2 B:TYR346 4.8 39.8 1.0 CD1 B:TYR346 4.9 38.7 1.0

N.Malhotra, Y.Manickam, A.Sharma. Tgprs with Inhibitors To Be Published.