|
Atomistry » Chlorine » PDB 7x8f-7xov » 7xnc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7x8f-7xov » 7xnc » |
Chlorine in PDB 7xnc: MEK1 Bound to DS94070624Enzymatic activity of MEK1 Bound to DS94070624
All present enzymatic activity of MEK1 Bound to DS94070624:
2.7.12.2; Protein crystallography data
The structure of MEK1 Bound to DS94070624, PDB code: 7xnc
was solved by
S.Kishikawa,
K.Takano,
O.Ubukata,
H.Hanzawa,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7xnc:
The structure of MEK1 Bound to DS94070624 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the MEK1 Bound to DS94070624
(pdb code 7xnc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the MEK1 Bound to DS94070624, PDB code: 7xnc: Chlorine binding site 1 out of 1 in 7xncGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the MEK1 Bound to DS94070624
![]() Mono view ![]() Stereo pair view
Reference:
K.Takano,
Y.Munehira,
M.Hatanaka,
R.Murakami,
Y.Shibata,
T.Shida,
K.Takeuchi,
S.Takechi,
T.Tabata,
T.Shimada,
S.Kishikawa,
Y.Matsui,
O.Ubukata,
T.Seki,
Y.Kaneta.
Discovery of A Novel Atp-Competitive Mek Inhibitor DS03090629 That Overcomes Resistance Conferred By Braf Overexpression in Braf-Mutated Melanoma. Mol.Cancer Ther. 2023.
Page generated: Sun Jul 13 08:26:57 2025
ISSN: ESSN 1538-8514 PubMed: 36622773 DOI: 10.1158/1535-7163.MCT-22-0306 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |