Chlorine in PDB 8ewa: Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923

Enzymatic activity of Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923

All present enzymatic activity of Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923:
6.3.2.8;

Protein crystallography data

The structure of Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923, PDB code: 8ewa was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.24 / 1.85
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 71.27, 76.95, 110.23, 90, 90, 90
R / Rfree (%) 16.7 / 21.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923 (pdb code 8ewa). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923, PDB code: 8ewa:

Chlorine binding site 1 out of 1 in 8ewa

Go back to Chlorine Binding Sites List in 8ewa
Chlorine binding site 1 out of 1 in the Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N- Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl403

b:47.9
occ:1.00
 N B:GLY30 3.4 25.9 1.0
CA B:GLY27 3.5 36.0 1.0
CA B:GLY30 3.6 27.2 1.0
N B:LEU152 3.6 24.6 1.0
N B:GLY27 3.6 36.8 1.0
O B:GLY27 3.9 34.8 1.0
C B:GLY27 3.9 33.9 1.0
CA B:ARG151 3.9 28.1 1.0
C B:ARG151 4.3 23.6 1.0
CD B:ARG151 4.3 40.0 1.0
SG B:CYS29 4.3 38.6 1.0
CB B:ARG151 4.3 30.5 1.0
CB B:LEU152 4.5 24.2 1.0
O B:LEU152 4.5 24.2 1.0
CA B:LEU152 4.5 23.3 1.0
O B:GLY150 4.6 34.0 1.0
C B:GLY30 4.6 23.2 1.0
C B:CYS29 4.7 25.9 1.0
CD1 B:LEU152 4.7 32.0 1.0
N B:ILE31 4.8 20.3 1.0
N B:CYS29 4.8 26.9 1.0
N B:MET28 4.9 32.5 1.0
C B:ALA26 4.9 35.5 1.0
CG B:ARG151 5.0 35.7 1.0

Reference:

J.Abendroth, P.Hill, P.S.Horanyi, D.D.Lorimer, T.E.Edwards. Crystal Structure of Udp-N-Acetylmuramate-L-Alanine Ligase (Udp-N-Acetylmuramoyl-L-Alanine Synthetase, Murc) Pseudomonas Aeruginosa in Complex with Ligand Az-13644923 To Be Published.
Page generated: Tue Jul 30 09:05:02 2024

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