Chlorine in PDB 8fr3: E. Coli Ef-Tu in Complex with Kkl-55

The structure of E. Coli Ef-Tu in Complex with Kkl-55, PDB code: 8fr3 was solved by H.A.Nguyen, A.B.Kuzmishin Nagy, C.M.Dunham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	64.82 / 2.23
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	59.385, 65.222, 70.559, 107.67, 98.79, 107.08
R / Rfree (%)	24.5 / 27.5

The structure of E. Coli Ef-Tu in Complex with Kkl-55 also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the E. Coli Ef-Tu in Complex with Kkl-55 (pdb code 8fr3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the E. Coli Ef-Tu in Complex with Kkl-55, PDB code: 8fr3:

Chlorine binding site 1 out of 1 in the E. Coli Ef-Tu in Complex with Kkl-55


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of E. Coli Ef-Tu in Complex with Kkl-55 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:114.9 occ:1.00 CL01 A:Y7C503 0.0 114.9 1.0 C02 A:Y7C503 1.8 104.6 1.0 C03 A:Y7C503 2.7 105.1 1.0 C18 A:Y7C503 2.7 98.5 1.0 NH1 A:ARG318 3.8 87.4 1.0 CD1 A:TYR326 4.0 72.8 1.0 C04 A:Y7C503 4.0 104.4 1.0 C06 A:Y7C503 4.0 100.5 1.0 NH2 A:ARG318 4.1 82.9 1.0 CE1 A:TYR326 4.3 76.1 1.0 CZ A:ARG318 4.4 83.4 1.0 C05 A:Y7C503 4.5 103.6 1.0 CB A:PHE322 4.7 75.1 1.0

N.Marathe, H.A.Nguyen, J.N.Alumasa, A.B.Kuzmishin Nagy, M.Vazquez, C.M.Dunham, K.C.Keiler. Antibiotic That Inhibits Trans -Translation Blocks Binding of Ef-Tu to Tmrna But Not to Trna. Mbio 46123 2023.
ISSN: ESSN 2150-7511
PubMed: 37681945
DOI: 10.1128/MBIO.01461-23