Chlorine in PDB 8hx7: Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine

Enzymatic activity of Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine

All present enzymatic activity of Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine:
2.6.1.85;

Protein crystallography data

The structure of Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine, PDB code: 8hx7 was solved by Y.Nakamichi, M.Watanabe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.11 / 1.95
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 98.291, 170.915, 160.344, 90, 90, 90
R / Rfree (%) 21 / 24

Other elements in 8hx7:

The structure of Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine also contains other interesting chemical elements:

Magnesium (Mg) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine (pdb code 8hx7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine, PDB code: 8hx7:

Chlorine binding site 1 out of 1 in 8hx7

Go back to Chlorine Binding Sites List in 8hx7
Chlorine binding site 1 out of 1 in the Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of 4-Amino-4-Deoxychorismate Synthase From Streptomyces Venezuelae Co-Crystallized with L-Glutamine within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl704

b:78.7
occ:1.00
O A:HOH858 3.0 46.8 1.0
OH B:TYR19 3.1 48.1 1.0
NH2 B:ARG178 3.2 50.9 1.0
O A:HOH861 3.5 52.1 1.0
CZ B:TYR19 4.0 46.9 1.0
NH1 B:ARG178 4.0 48.4 1.0
CZ B:ARG178 4.1 49.8 1.0
CE1 B:TYR19 4.1 47.7 1.0
O A:VAL549 4.1 46.5 1.0
NH2 A:ARG537 4.3 48.5 1.0
CD1 B:ILE172 4.4 51.4 1.0
NE2 B:GLN18 4.5 55.4 1.0
CA A:HIS550 4.6 45.8 1.0
CB A:HIS550 4.8 47.0 1.0
NE A:ARG537 4.9 46.8 1.0
O B:HOH821 4.9 49.4 1.0

Reference:

Y.Nakamichi, J.Kobayashi, K.Toyoda, M.Suda, K.Hiraga, M.Inui, M.Watanabe. Structural Basis For the Allosteric Pathway of 4-Amino-4-Deoxychorismate Synthase. Acta Crystallogr D Struct V. 79 895 2023BIOL.
ISSN: ISSN 2059-7983
PubMed: 37712435
DOI: 10.1107/S2059798323006320
Page generated: Tue Jul 30 10:25:44 2024

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