Chlorine in PDB 8kfq: The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6

The structure of The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6, PDB code: 8kfq was solved by C.Wu, L.Ouyang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.53 / 3.22
Space group	I 2 3
Cell size a, b, c (Å), α, β, γ (°)	145.5, 145.5, 145.5, 90, 90, 90
R / Rfree (%)	20 / 26

The binding sites of Chlorine atom in the The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6 (pdb code 8kfq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6, PDB code: 8kfq:

Chlorine binding site 1 out of 1 in the The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Egfr(T797M/L858R) with Small Molecule Inhibitor B6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1102 b:83.0 occ:1.00 CL01 A:VUZ1102 0.0 83.0 1.0 C02 A:VUZ1102 1.8 65.3 1.0 C03 A:VUZ1102 2.7 63.7 1.0 C31 A:VUZ1102 2.8 65.0 1.0 CE A:MET790 2.8 89.9 1.0 O A:THR854 3.9 67.7 1.0 C04 A:VUZ1102 4.0 56.6 1.0 C30 A:VUZ1102 4.1 62.1 1.0 CE A:MET766 4.2 88.5 1.0 SD A:MET790 4.3 103.6 1.0 CB A:THR854 4.5 68.0 1.0 C05 A:VUZ1102 4.6 57.8 1.0 OG1 A:THR854 4.8 66.7 1.0 C A:THR854 4.9 65.4 1.0 CD1 A:LEU844 5.0 60.7 1.0 CG A:MET790 5.0 74.0 1.0

C.Wu, L.Ouyang. Structure of Egfr(T979M/L858R) with Small Molecule Inhibitor B6 To Be Published.