Chlorine in PDB 8okf: Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide

All present enzymatic activity of Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide:
2.5.1.18;

The structure of Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide, PDB code: 8okf was solved by E.Wolf, A.Boergel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.11 / 1.85
Space group	P 42 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.152, 78.152, 101.748, 90, 90, 90
R / Rfree (%)	16.5 / 20.1

The binding sites of Chlorine atom in the Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide (pdb code 8okf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide, PDB code: 8okf:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:35.6 occ:1.00 OG A:SER218 2.6 15.3 1.0 ND2 A:ASN257 2.7 14.8 1.0 N A:ILE262 2.8 15.5 1.0 O A:ILE262 2.9 15.9 1.0 CB A:ALA232 3.3 15.0 1.0 CB A:SER218 3.3 16.3 1.0 CA A:ILE262 3.5 16.4 1.0 CB A:ILE262 3.6 16.1 1.0 C A:ILE262 3.6 16.3 1.0 CG A:ASN257 3.6 17.0 1.0 O A:TYR260 3.6 16.1 1.0 OD1 A:ASN257 3.8 18.9 1.0 C A:CYS261 3.8 16.9 1.0 CA A:CYS261 4.0 16.4 1.0 CB A:PHE219 4.2 15.5 1.0 C A:SER218 4.2 15.0 1.0 O A:SER218 4.3 15.6 1.0 CG1 A:ILE262 4.3 16.4 1.0 CA A:SER218 4.3 14.7 1.0 CD2 A:LEU234 4.5 16.4 1.0 O A:HOH542 4.6 27.9 1.0 C A:TYR260 4.6 17.0 1.0 N A:PHE219 4.6 14.4 1.0 CA A:ALA232 4.7 15.6 1.0 CG2 A:ILE262 4.7 18.1 1.0 N A:CYS261 4.8 15.7 1.0 C A:ALA232 4.9 15.2 1.0 N A:PHE263 4.9 15.6 1.0 CB A:ASN257 5.0 17.5 1.0

Chlorine binding site 2 out of 2 in the Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Wd Repeat Containing Protein 5 (WDR5)- PER2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:36.2 occ:1.00 N A:PHE79 3.0 16.1 1.0 CB A:PHE79 3.6 18.1 1.0 CA A:LYS78 3.8 19.1 1.0 C A:LYS78 3.9 18.0 1.0 CA A:PHE79 3.9 17.3 1.0 O A:GLY77 4.3 23.1 1.0 CB A:LYS78 4.6 22.5 1.0 O A:HOH579 4.7 17.7 1.0 O A:PHE79 4.8 15.1 1.0 N A:LYS78 4.9 18.6 1.0 C A:PHE79 4.9 17.7 1.0 CG A:PHE79 5.0 18.5 1.0 C A:GLY77 5.0 21.5 1.0

E.Wolf, A.Boergel, A.Rawleigh, M.Conrady, F.Hof, K.Ricci, S.Brown. A Structural Competition Involving WDR5 Times Circadian Oscillations To Be Published.