Atomistry » Chlorine » PDB 8pah-8pkx » 8pd1
Atomistry »
  Chlorine »
    PDB 8pah-8pkx »
      8pd1 »

Chlorine in PDB 8pd1: Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide

Enzymatic activity of Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide

All present enzymatic activity of Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide:
2.3.1.179;

Protein crystallography data

The structure of Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide, PDB code: 8pd1 was solved by C.Georgiou, R.Brenk, V.Yadrykhinsky, L.O.Espeland, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.71 / 1.87
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 100.99, 103.76, 141.61, 90, 90, 90
R / Rfree (%) 15.8 / 19.6

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide (pdb code 8pd1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide, PDB code: 8pd1:

Chlorine binding site 1 out of 1 in 8pd1

Go back to Chlorine Binding Sites List in 8pd1
Chlorine binding site 1 out of 1 in the Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Pseudomonas Aeruginosa Fabf C164A Mutant in Complex with N-Isopropyl- 1H-Imidazole-4-Carboxamide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl513

b:75.3
occ:1.00
 N B:MET270 3.0 46.2 1.0
CD2 B:HIS269 3.6 56.0 1.0
CG B:MET270 3.6 74.6 1.0
CB B:MET270 3.7 61.0 1.0
CA B:HIS269 3.7 44.7 1.0
CG B:HIS269 3.8 56.2 1.0
C B:HIS269 3.8 44.5 1.0
NE2 B:HIS269 3.8 63.4 1.0
CA B:MET270 3.9 55.0 1.0
ND1 B:HIS269 4.1 64.2 1.0
CE1 B:HIS269 4.2 69.4 1.0
CB B:HIS269 4.4 48.1 1.0
SD B:MET270 4.6 87.6 1.0
O B:PHE268 4.9 43.3 1.0
N B:HIS269 4.9 38.7 1.0
O B:HIS269 5.0 41.3 1.0

Reference:

C.Georgiou, L.O.Espeland, H.Bukya, V.Yadrykhinsky, B.E.Haug, P.Mainkar, R.Brenk. New Starting Points For Antibiotics Targeting P. Aeruginosa Fabf Discovered By Crystallographic Fragment Screening Followed By Hit Expansion Chemrxiv 2023.
ISSN: ISSN 2573-2293
DOI: 10.26434/CHEMRXIV-2023-CWK25
Page generated: Sun Jul 13 13:07:20 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy