Chlorine in PDB 8ql0: Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo

All present enzymatic activity of Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo:
3.5.3.15;

The structure of Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo, PDB code: 8ql0 was solved by F.M.Ranaivoson, E.Beaumont, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	101.20 / 1.68
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	127.323, 54.318, 106.785, 90, 108.61, 90
R / Rfree (%)	19.7 / 24.1

The binding sites of Chlorine atom in the Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo (pdb code 8ql0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo, PDB code: 8ql0:

Chlorine binding site 1 out of 1 in the Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human PAD6 Phosphomimic Mutant V10E/S446E, Apo within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl706 b:43.0 occ:1.00 O A:HOH1051 2.9 36.9 1.0 NH2 A:ARG301 3.1 23.1 1.0 OE1 A:GLN464 3.6 37.4 1.0 NH1 A:ARG301 3.8 22.7 1.0 CZ A:ARG301 3.9 23.5 1.0 CB A:SER270 4.0 29.7 1.0 O A:SER270 4.0 26.1 1.0 CD A:GLN464 4.6 33.8 1.0 OG A:SER270 4.6 30.2 1.0 CD1 A:LEU272 4.6 25.3 1.0 C A:SER270 4.7 25.6 1.0 O A:HOH957 4.7 23.0 1.0 CA A:SER270 4.7 27.4 1.0 NE2 A:GLN464 4.9 34.1 1.0 CG A:LEU272 4.9 24.6 1.0

F.M.Ranaivoson, R.Bande, I.Cardaun, A.De Riso, A.Gartner, P.Loke, C.Reinisch, P.Vogirala, E.Beaumont. Crystal Structure of Human Peptidylarginine Deiminase Type VI (PAD6) Provides Insights Into Its Inactivity. Iucrj 2024.
ISSN: ESSN 2052-2525
PubMed: 38656308
DOI: 10.1107/S2052252524002549