Chlorine in PDB 8r38: BIIG2 Anti-Integrin Fab

The structure of BIIG2 Anti-Integrin Fab, PDB code: 8r38 was solved by G.Cordara, J.B.Heim, H.Johannesen, U.Krengel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.38 / 1.38
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	62.93, 80.882, 87.469, 90, 90, 90
R / Rfree (%)	19.5 / 21.7

The binding sites of Chlorine atom in the BIIG2 Anti-Integrin Fab (pdb code 8r38). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the BIIG2 Anti-Integrin Fab, PDB code: 8r38:

Chlorine binding site 1 out of 1 in the BIIG2 Anti-Integrin Fab


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of BIIG2 Anti-Integrin Fab within 5.0Å range: probe atom residue distance (Å) B Occ L:Cl305 b:28.9 occ:1.00 N L:SER30 3.3 19.9 1.0 CA L:SER30 3.5 20.5 1.0 CB L:ARG28 3.6 20.6 0.6 CB L:ARG28 3.7 24.8 0.4 CA L:GLY68 3.8 19.6 1.0 CD L:ARG28 3.8 31.6 0.4 CG L:ARG28 4.0 25.8 0.4 CD L:ARG28 4.1 26.3 0.6 CB L:SER30 4.2 23.1 1.0 N L:GLY68 4.2 18.9 1.0 NE L:ARG28 4.3 33.3 0.6 CG L:ARG28 4.3 22.3 0.6 N L:ILE29 4.4 19.8 1.0 C L:ARG28 4.4 20.9 0.4 C L:ILE29 4.6 19.4 1.0 CA L:ARG28 4.6 22.5 0.4 CA L:ARG28 4.6 20.0 0.6 C L:ARG28 4.6 19.4 0.6 C L:SER30 4.7 18.1 1.0 O L:ARG28 4.7 22.6 0.4 C L:GLY68 4.8 19.4 1.0 O L:SER30 4.8 21.3 1.0 OG L:SER30 4.8 22.4 1.0 OG L:SER67 4.9 25.6 1.0 O L:GLY68 4.9 20.6 1.0

A.Nguyen, J.B.Heim, G.Cordara, M.C.Charlesworth, M.Li, H.Johannesen, M.C.Chan, C.M.Azumaya, B.Madden, U.Krengel, M.G.Campbell, A.Meves. Structural and Functional Characterization of Integrin ALPHA5-Targeting Antibodies For Anti-Angiogenic Therapy To Be Published.