Chlorine in PDB 8raz: The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3

The structure of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3, PDB code: 8raz was solved by M.Thomsen, E.Costanzi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.39 / 2.84
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	70.32, 92.414, 94.216, 67.13, 86.69, 75.82
R / Rfree (%)	21.4 / 27.9

The binding sites of Chlorine atom in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 (pdb code 8raz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3, PDB code: 8raz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1003 b:90.2 occ:1.00 O A:ALA791 3.5 76.7 1.0 CA A:PRO795 3.8 70.9 1.0 N A:PRO795 3.9 70.9 1.0 O A:ASN792 4.0 77.1 1.0 CG A:PRO795 4.1 71.9 1.0 CD A:PRO795 4.2 72.1 1.0 C A:ASN792 4.3 73.6 1.0 CB A:PRO795 4.3 71.8 1.0 C A:ILE794 4.4 68.0 1.0 CA A:ASN792 4.5 74.5 1.0 O A:ILE794 4.6 66.0 1.0 C A:ALA791 4.6 72.0 1.0 N A:ILE794 4.9 67.5 1.0

Chlorine binding site 2 out of 2 in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_E749A/MSH3_E976A) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1204 b:100.8 occ:1.00 CD B:ARG616 3.7 80.1 1.0 CG B:ARG616 3.9 76.6 1.0 CB B:ARG616 4.1 72.0 1.0 NH1 B:ARG616 4.2 80.9 1.0 NZ B:LYS568 4.5 56.2 1.0 NE B:ARG616 4.7 82.0 1.0 CG B:LYS617 4.9 72.5 1.0 CZ B:ARG616 4.9 82.5 1.0 CA B:ARG616 4.9 67.7 1.0 O B:HOH1305 5.0 32.1 1.0 CE B:LYS617 5.0 72.6 1.0

M.Thomsen, T.Neudegger, G.Thieulin-Pardo, M.Blaesse, E.Costanzi, S.Steinbacher, N.V.Plotnikov, C.Dominguez, R.R.Iyer, H.A.Wilkinson, E.Monteagudo, T.S.Haque, B.C.Prasad, M.Finley, J.Boudet, T.F.Vogt, D.P.Felsenfeld. The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2/MSH3) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 To Be Published.