Chlorine in PDB 8rb1: The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3

The structure of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3, PDB code: 8rb1 was solved by M.Thomsen, E.Costanzi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.66 / 2.09
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	69.705, 91.681, 94.024, 67.34, 87.16, 75.86
R / Rfree (%)	19.8 / 23.5

The structure of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 (pdb code 8rb1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3, PDB code: 8rb1:

Chlorine binding site 1 out of 1 in the The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2_K675R/MSH3_K902R) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1208 b:94.8 occ:1.00 CE1 B:HIS826 4.1 51.8 1.0 CB B:CYS822 4.1 44.5 1.0 SG B:CYS822 4.1 46.6 1.0 OH B:TYR818 4.2 46.8 1.0 NE2 B:HIS826 4.3 50.1 1.0 O B:THR397 4.4 50.2 1.0 O B:HOH1365 4.5 58.9 1.0 O B:GLY398 4.5 49.6 1.0 CE2 B:TYR818 4.6 48.9 1.0 CZ B:TYR818 4.6 46.7 1.0 C B:GLY398 4.8 48.9 1.0

M.Thomsen, T.Neudegger, G.Thieulin-Pardo, M.Blaesse, E.Costanzi, S.Steinbacher, N.V.Plotnikov, C.Dominguez, R.R.Iyer, H.A.Wilkinson, E.Monteagudo, T.S.Haque, B.C.Prasad, M.Finley, J.Boudet, T.F.Vogt, D.P.Felsenfeld. The Crystal Structure of Dna-Bound Human Mutsbeta (MSH2/MSH3) in the Canonical Mismatch Bound Conformation with Adp Bound in MSH2 and MSH3 To Be Published.