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Atomistry » Chlorine » PDB 8sbx-8sxr » 8skl | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8sbx-8sxr » 8skl » |
Chlorine in PDB 8skl: PTP1B in Complex with 182Enzymatic activity of PTP1B in Complex with 182
All present enzymatic activity of PTP1B in Complex with 182:
3.1.3.48; Protein crystallography data
The structure of PTP1B in Complex with 182, PDB code: 8skl
was solved by
J.J.Babon,
H.Chen,
T.Tiganis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8skl:
The structure of PTP1B in Complex with 182 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the PTP1B in Complex with 182
(pdb code 8skl). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the PTP1B in Complex with 182, PDB code: 8skl: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 8sklGo back to Chlorine Binding Sites List in 8skl
Chlorine binding site 1 out
of 2 in the PTP1B in Complex with 182
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 8sklGo back to Chlorine Binding Sites List in 8skl
Chlorine binding site 2 out
of 2 in the PTP1B in Complex with 182
Mono view Stereo pair view
Reference:
S.Liang,
E.Tran,
X.Du,
J.Dong,
H.Sudholz,
H.Chen,
Z.Qu,
N.Huntington,
J.Babon,
N.Kershaw,
Z.Y.Zhang,
J.Baell,
F.Wiede,
T.Tiganis.
A Small Molecule Inhibitor of PTP1B and PTPN2 Enhances T Cell Anti-Tumor Immunity. Biorxiv 2023.
Page generated: Thu Dec 28 03:29:50 2023
ISSN: ISSN 2692-8205 PubMed: 37397992 DOI: 10.1101/2023.06.16.545220 |
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