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Atomistry » Chlorine » PDB 8sbx-8sxr » 8spd | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8sbx-8sxr » 8spd » |
Chlorine in PDB 8spd: Cytochrome P450 (Cyp) 3A4 Crystallized with ClotrimazoleEnzymatic activity of Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole
All present enzymatic activity of Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole:
1.14.14.1; 1.14.14.55; 1.14.14.56; 1.14.14.73; Protein crystallography data
The structure of Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole, PDB code: 8spd
was solved by
M.H.Hsu,
E.F.Johnson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8spd:
The structure of Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole
(pdb code 8spd). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole, PDB code: 8spd: Chlorine binding site 1 out of 1 in 8spdGo back to Chlorine Binding Sites List in 8spd
Chlorine binding site 1 out
of 1 in the Cytochrome P450 (Cyp) 3A4 Crystallized with Clotrimazole
Mono view Stereo pair view
Reference:
M.H.Hsu,
E.F.Johnson.
Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochrome P450 (Cyp) 3A5 and 3A4. Drug Metab.Dispos. 2023.
Page generated: Thu Dec 28 03:30:17 2023
ISSN: ESSN 1521-009X PubMed: 37770228 DOI: 10.1124/DMD.123.001464 |
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