Chlorine in PDB 8sw6: Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3

Enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3

All present enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3:
3.1.3.16;

Protein crystallography data

The structure of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3, PDB code: 8sw6 was solved by M.S.Choy, W.Peti, R.Page, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.59 / 1.76
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 92.004, 92.004, 199.581, 90, 90, 90
R / Rfree (%) 17.5 / 20.8

Other elements in 8sw6:

The structure of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 also contains other interesting chemical elements:

Manganese (Mn) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 (pdb code 8sw6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3, PDB code: 8sw6:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 1 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:40.5
occ:1.00
 N A:GLY215 3.0 31.7 1.0
O A:HOH747 3.2 41.0 1.0
N A:GLU230 3.2 28.5 1.0
N A:VAL231 3.4 29.6 1.0
CB A:GLU230 3.4 34.9 1.0
CA A:GLY228 3.4 30.0 1.0
C A:GLY228 3.5 31.2 1.0
CA A:GLU230 3.7 34.2 1.0
N A:ALA229 3.7 26.2 1.0
CA A:GLY215 3.8 30.7 1.0
C A:GLN214 3.9 41.1 1.0
CA A:GLN214 3.9 47.1 1.0
N A:GLY228 3.9 24.3 1.0
CG2 A:VAL231 3.9 29.3 1.0
O A:GLY228 3.9 27.3 1.0
C A:GLU230 4.0 30.8 1.0
O A:VAL213 4.0 41.5 1.0
OE1 A:GLN214 4.1 91.8 1.0
O A:GLY215 4.2 29.6 1.0
C A:ALA229 4.3 26.8 1.0
CB A:VAL231 4.5 30.5 1.0
CA A:VAL231 4.5 25.8 1.0
C A:GLY215 4.5 34.5 1.0
CA A:ALA229 4.6 25.5 1.0
CG A:GLU230 4.7 59.1 1.0
C A:VAL213 4.8 42.2 1.0
N A:GLN214 4.8 37.9 1.0
O A:HOH616 4.8 39.6 1.0
CB A:GLN214 4.9 53.0 1.0
O A:HOH778 4.9 58.0 1.0
CD A:GLN214 5.0 83.2 1.0

Chlorine binding site 2 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 2 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl406

b:36.1
occ:1.00
 O A:HOH735 3.2 45.5 1.0
N A:ASN86 3.3 28.3 1.0
O A:HOH701 3.5 40.0 1.0
CA A:SER85 3.7 29.4 1.0
CA A:LEU59 3.7 31.7 1.0
C A:PRO58 3.8 28.7 1.0
O A:PRO58 3.8 26.7 1.0
N A:LEU59 3.8 29.4 1.0
CB A:SER85 3.8 31.8 1.0
CB A:PRO58 4.0 29.7 1.0
C A:SER85 4.0 26.9 1.0
CB A:ASN86 4.1 24.8 1.0
O A:ASN86 4.1 24.5 1.0
ND2 A:ASN86 4.1 30.5 1.0
CG A:PRO58 4.2 36.0 1.0
CA A:ASN86 4.2 28.5 1.0
C A:LEU59 4.3 28.8 1.0
OG A:SER85 4.3 37.8 1.0
CG A:ASN86 4.3 30.2 1.0
CG A:LYS60 4.4 38.4 1.0
O A:HOH512 4.5 57.7 1.0
CA A:PRO58 4.6 34.1 1.0
N A:LYS60 4.6 26.6 1.0
C A:ASN86 4.6 28.9 1.0
O A:LEU59 4.8 29.5 1.0
CE A:LYS60 4.9 36.1 1.0
O A:GLU84 4.9 34.8 1.0
CB A:LEU59 5.0 30.4 1.0

Chlorine binding site 3 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 3 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl404

b:43.0
occ:1.00
 N B:GLY215 3.1 38.1 1.0
O B:HOH685 3.2 47.6 1.0
N B:GLU230 3.2 39.7 1.0
N B:VAL231 3.4 36.1 1.0
CA B:GLY228 3.5 33.5 1.0
C B:GLY228 3.5 37.3 1.0
CB B:GLU230 3.5 42.3 1.0
N B:ALA229 3.7 36.3 1.0
CA B:GLU230 3.7 42.2 1.0
CG2 B:VAL231 3.8 32.7 1.0
CA B:GLY215 3.9 36.5 1.0
O B:GLY228 3.9 34.0 1.0
N B:GLY228 3.9 36.5 1.0
C B:GLU230 4.0 44.4 1.0
CA B:GLN214 4.0 48.6 1.0
C B:GLN214 4.0 44.5 1.0
O B:VAL213 4.1 46.3 1.0
C B:ALA229 4.3 39.2 1.0
O B:GLY215 4.3 34.6 1.0
CB B:VAL231 4.5 39.9 1.0
CA B:VAL231 4.5 34.4 1.0
CA B:ALA229 4.6 36.9 1.0
C B:GLY215 4.6 33.0 1.0
O B:HOH690 4.8 54.9 1.0
C B:VAL213 4.9 44.7 1.0
N B:GLN214 4.9 42.6 1.0
CB B:GLN214 4.9 50.2 1.0

Reference:

M.S.Choy, H.T.Nguyen, A.N.Kettenbach, W.Peti, R.Page. A Protein Phosphatase 1 Specific Phosphatase Targeting Peptide (Phostap) to Identify the PP1 Phosphatome To Be Published.
Page generated: Tue Jul 30 12:38:35 2024

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