Chlorine in PDB 8sw6: Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3

Enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3

All present enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3:
3.1.3.16;

Protein crystallography data

The structure of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3, PDB code: 8sw6 was solved by M.S.Choy, W.Peti, R.Page, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.59 / 1.76
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 92.004, 92.004, 199.581, 90, 90, 90
R / Rfree (%) 17.5 / 20.8

Other elements in 8sw6:

The structure of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 also contains other interesting chemical elements:

Manganese (Mn) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 (pdb code 8sw6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3, PDB code: 8sw6:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 1 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:40.5
occ:1.00
 N A:GLY215 3.0 31.7 1.0
O A:HOH747 3.2 41.0 1.0
N A:GLU230 3.2 28.5 1.0
N A:VAL231 3.4 29.6 1.0
CB A:GLU230 3.4 34.9 1.0
CA A:GLY228 3.4 30.0 1.0
C A:GLY228 3.5 31.2 1.0
CA A:GLU230 3.7 34.2 1.0
N A:ALA229 3.7 26.2 1.0
CA A:GLY215 3.8 30.7 1.0
C A:GLN214 3.9 41.1 1.0
CA A:GLN214 3.9 47.1 1.0
N A:GLY228 3.9 24.3 1.0
CG2 A:VAL231 3.9 29.3 1.0
O A:GLY228 3.9 27.3 1.0
C A:GLU230 4.0 30.8 1.0
O A:VAL213 4.0 41.5 1.0
OE1 A:GLN214 4.1 91.8 1.0
O A:GLY215 4.2 29.6 1.0
C A:ALA229 4.3 26.8 1.0
CB A:VAL231 4.5 30.5 1.0
CA A:VAL231 4.5 25.8 1.0
C A:GLY215 4.5 34.5 1.0
CA A:ALA229 4.6 25.5 1.0
CG A:GLU230 4.7 59.1 1.0
C A:VAL213 4.8 42.2 1.0
N A:GLN214 4.8 37.9 1.0
O A:HOH616 4.8 39.6 1.0
CB A:GLN214 4.9 53.0 1.0
O A:HOH778 4.9 58.0 1.0
CD A:GLN214 5.0 83.2 1.0

Chlorine binding site 2 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 2 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl406

b:36.1
occ:1.00
 O A:HOH735 3.2 45.5 1.0
N A:ASN86 3.3 28.3 1.0
O A:HOH701 3.5 40.0 1.0
CA A:SER85 3.7 29.4 1.0
CA A:LEU59 3.7 31.7 1.0
C A:PRO58 3.8 28.7 1.0
O A:PRO58 3.8 26.7 1.0
N A:LEU59 3.8 29.4 1.0
CB A:SER85 3.8 31.8 1.0
CB A:PRO58 4.0 29.7 1.0
C A:SER85 4.0 26.9 1.0
CB A:ASN86 4.1 24.8 1.0
O A:ASN86 4.1 24.5 1.0
ND2 A:ASN86 4.1 30.5 1.0
CG A:PRO58 4.2 36.0 1.0
CA A:ASN86 4.2 28.5 1.0
C A:LEU59 4.3 28.8 1.0
OG A:SER85 4.3 37.8 1.0
CG A:ASN86 4.3 30.2 1.0
CG A:LYS60 4.4 38.4 1.0
O A:HOH512 4.5 57.7 1.0
CA A:PRO58 4.6 34.1 1.0
N A:LYS60 4.6 26.6 1.0
C A:ASN86 4.6 28.9 1.0
O A:LEU59 4.8 29.5 1.0
CE A:LYS60 4.9 36.1 1.0
O A:GLU84 4.9 34.8 1.0
CB A:LEU59 5.0 30.4 1.0

Chlorine binding site 3 out of 3 in 8sw6

Go back to Chlorine Binding Sites List in 8sw6
Chlorine binding site 3 out of 3 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl404

b:43.0
occ:1.00
 N B:GLY215 3.1 38.1 1.0
O B:HOH685 3.2 47.6 1.0
N B:GLU230 3.2 39.7 1.0
N B:VAL231 3.4 36.1 1.0
CA B:GLY228 3.5 33.5 1.0
C B:GLY228 3.5 37.3 1.0
CB B:GLU230 3.5 42.3 1.0
N B:ALA229 3.7 36.3 1.0
CA B:GLU230 3.7 42.2 1.0
CG2 B:VAL231 3.8 32.7 1.0
CA B:GLY215 3.9 36.5 1.0
O B:GLY228 3.9 34.0 1.0
N B:GLY228 3.9 36.5 1.0
C B:GLU230 4.0 44.4 1.0
CA B:GLN214 4.0 48.6 1.0
C B:GLN214 4.0 44.5 1.0
O B:VAL213 4.1 46.3 1.0
C B:ALA229 4.3 39.2 1.0
O B:GLY215 4.3 34.6 1.0
CB B:VAL231 4.5 39.9 1.0
CA B:VAL231 4.5 34.4 1.0
CA B:ALA229 4.6 36.9 1.0
C B:GLY215 4.6 33.0 1.0
O B:HOH690 4.8 54.9 1.0
C B:VAL213 4.9 44.7 1.0
N B:GLN214 4.9 42.6 1.0
CB B:GLN214 4.9 50.2 1.0

Reference:

M.S.Choy, H.T.Nguyen, A.N.Kettenbach, W.Peti, R.Page. A Protein Phosphatase 1 Specific Phosphatase Targeting Peptide (Phostap) to Identify the PP1 Phosphatome To Be Published.
Page generated: Tue Jul 30 12:38:35 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy