Chlorine in PDB 8upn: Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb

Enzymatic activity of Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb

All present enzymatic activity of Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb:
1.1.1.86;

Protein crystallography data

The structure of Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb, PDB code: 8upn was solved by X.Lin, T.Lonhienne, L.W.Guddat, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.74 / 2.59
Space group I 2 3
Cell size a, b, c (Å), α, β, γ (°) 130.72, 130.72, 130.72, 90, 90, 90
R / Rfree (%) 20.1 / 24.6

Other elements in 8upn:

The structure of Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb (pdb code 8upn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb, PDB code: 8upn:

Chlorine binding site 1 out of 1 in 8upn

Go back to Chlorine Binding Sites List in 8upn
Chlorine binding site 1 out of 1 in the Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Campylobacter Jejuni Ketol-Acid Reductoisomerase in Complex with Nadp+ and Hmkb within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl403

b:165.5
occ:0.33
NH2 A:ARG297 2.8 101.1 1.0
CZ A:ARG297 3.2 98.1 1.0
NE A:ARG297 3.5 95.4 1.0
NH1 A:ARG297 4.1 98.3 1.0
CB A:ARG297 4.1 86.2 1.0
CG A:ARG297 4.6 87.7 1.0
CD A:ARG297 4.6 91.0 1.0

Reference:

X.Lin, T.Lonhienne, Y.Lv, J.Kurz, R.Mcgeary, G.Schenk, L.W.Guddat. Mapping of the Reaction Trajectory Catalyzed By Class I Ketol-Acid Reductoisomerase Acs Catalysis 2024.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.4C00958
Page generated: Tue Jul 30 13:17:10 2024

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