Chlorine in PDB 8uuc: Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G)

The structure of Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G), PDB code: 8uuc was solved by C.H.Trasvina-Arenas, S.S.David, A.J.Fisher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.62 / 1.55
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	38.832, 84.137, 225.742, 90, 90, 90
R / Rfree (%)	17.6 / 19.7

The structure of Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G) also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Sodium	(Na)	2 atoms

The binding sites of Chlorine atom in the Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G) (pdb code 8uuc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G), PDB code: 8uuc:

Chlorine binding site 1 out of 1 in the Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Bacterial Clusterless Mutyx Bound to An Abasic Site Analog (Thf) Opposite D(8-Oxo-G) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:59.8 occ:1.00 O A:HOH597 3.3 53.5 1.0 O A:HOH422 3.3 52.0 1.0 N A:ARG208 3.4 26.2 1.0 O A:HOH536 3.5 49.3 1.0 O A:HOH503 3.5 27.6 1.0 CB A:SER207 3.8 29.9 1.0 CA A:SER207 3.8 30.6 1.0 O B:HOH221 4.0 38.8 1.0 OG A:SER202 4.1 42.2 1.0 C A:SER207 4.2 27.4 1.0 CB A:ARG208 4.2 27.2 1.0 HO2 A:EDO315 4.3 65.2 1.0 CA A:ARG208 4.4 24.5 1.0 O2 A:EDO315 4.7 54.3 1.0 CB A:SER202 4.9 44.0 1.0

C.H.Trasvina-Arenas, M.Hashemian, M.Malek, S.Merrill, A.J.Fisher, S.S.David. Crystal Structure of Mutyx: A Novel Clusterless Adenine Dna Glycosylase with A Distinct C-Terminal Domain and 8-Oxoguanine Recognition Sphere. Biorxiv 2025.
ISSN: ISSN 2692-8205
PubMed: 39803464
DOI: 10.1101/2025.01.03.631205