Chlorine in PDB 8wfi: Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation

The structure of Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation (pdb code 8wfi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation, PDB code: 8wfi:

Chlorine binding site 1 out of 1 in the Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Glycine Transporter 1 in Complex with Glycine in Occluded Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:26.1 occ:1.00 OG A:SER353 2.6 22.4 1.0 OG A:SER317 3.0 21.3 1.0 NE2 A:GLN313 3.2 22.2 1.0 CB A:SER317 3.4 21.3 1.0 OH A:TYR88 3.4 24.5 1.0 CB A:SER353 3.5 22.4 1.0 CD1 A:PHE72 3.9 24.7 1.0 O A:GLY67 3.9 21.4 1.0 CE2 A:TYR88 4.2 24.5 1.0 CD A:GLN313 4.2 22.2 1.0 CB A:PHE72 4.2 24.7 1.0 CZ A:TYR88 4.3 24.5 1.0 CG A:PHE72 4.3 24.7 1.0 CG A:GLN313 4.3 22.2 1.0 ND2 A:ASN349 4.4 23.2 1.0 ND2 A:ASN68 4.4 21.9 1.0 CE1 A:PHE72 4.6 24.7 1.0 CG A:ASN68 4.7 21.9 1.0 CA A:ASN68 4.7 21.9 1.0 O A:GLN313 4.8 22.2 1.0 C A:GLY67 4.8 21.4 1.0 CA A:SER317 4.9 21.3 1.0 CA A:SER353 4.9 22.4 1.0

Y.Wei, R.Li, Y.Meng, T.Hu, J.Zhao, Y.Gao, Q.Bai, N.Li, Y.Zhao. Transport Mechanism and Pharmacology of the Human GLYT1. Cell 2024.
ISSN: ISSN 1097-4172
PubMed: 38513663
DOI: 10.1016/J.CELL.2024.02.026