Chlorine in PDB 8x64: Cryoem Structure of the Histamine H1 Receptor-Bril/Anti Bril Fab Complex with Desloratadine

The binding sites of Chlorine atom in the Cryoem Structure of the Histamine H1 Receptor-Bril/Anti Bril Fab Complex with Desloratadine (pdb code 8x64). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryoem Structure of the Histamine H1 Receptor-Bril/Anti Bril Fab Complex with Desloratadine, PDB code: 8x64:

Chlorine binding site 1 out of 1 in the Cryoem Structure of the Histamine H1 Receptor-Bril/Anti Bril Fab Complex with Desloratadine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryoem Structure of the Histamine H1 Receptor-Bril/Anti Bril Fab Complex with Desloratadine within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:81.2 occ:1.00 CL01 B:Y5R601 0.0 81.2 1.0 C02 B:Y5R601 1.8 81.2 1.0 C03 B:Y5R601 2.7 81.2 1.0 C07 B:Y5R601 2.8 81.2 1.0 CZ3 B:TRP428 3.2 72.9 1.0 CE3 B:TRP428 3.4 72.9 1.0 C04 B:Y5R601 4.0 81.2 1.0 C06 B:Y5R601 4.1 81.2 1.0 CH2 B:TRP428 4.1 72.9 1.0 CE2 B:PHE432 4.1 80.0 1.0 ND2 B:ASN198 4.2 77.2 1.0 CB B:ILE115 4.2 67.6 1.0 CD2 B:TRP428 4.3 72.9 1.0 CG2 B:ILE115 4.3 67.6 1.0 CG1 B:ILE115 4.3 67.6 1.0 CZ B:PHE432 4.4 80.0 1.0 C05 B:Y5R601 4.6 81.2 1.0 O B:ASN198 4.7 77.2 1.0 CD1 B:PHE199 4.8 76.2 1.0 CZ2 B:TRP428 4.9 72.9 1.0 CD1 B:ILE115 4.9 67.6 1.0 CE2 B:TRP428 5.0 72.9 1.0

D.Wang, Q.Guo, Z.Wu, M.Li, B.He, Y.Du, K.Zhang, Y.Tao. Molecular Mechanism of Antihistamines Recognition and Regulation of the Histamine H 1 Receptor. Nat Commun V. 15 84 2024.
ISSN: ESSN 2041-1723
PubMed: 38167898
DOI: 10.1038/S41467-023-44477-4