Chlorine in PDB 8y2d: Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine

The structure of Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine (pdb code 8y2d). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine, PDB code: 8y2d:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Human Dopamine Transporter in Complex with Dopamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl704 b:43.7 occ:1.00 OG A:SER357 2.7 29.2 1.0 OG A:SER321 2.9 35.8 1.0 NE2 A:GLN317 3.2 10.9 1.0 OH A:TYR102 3.3 32.9 1.0 CB A:SER321 3.4 13.6 1.0 CB A:SER357 3.8 18.2 1.0 ND2 A:ASN353 3.9 25.4 1.0 CD1 A:PHE86 4.0 25.3 1.0 CE1 A:TYR102 4.0 27.5 1.0 CZ A:TYR102 4.1 31.4 1.0 ND2 A:ASN82 4.1 11.1 1.0 CD A:GLN317 4.2 20.0 1.0 CG A:GLN317 4.3 21.6 1.0 CG A:ASN82 4.3 20.7 1.0 O A:ALA81 4.4 33.1 1.0 CA A:ASN82 4.4 19.6 1.0 CB A:PHE86 4.5 20.2 1.0 CG A:PHE86 4.6 24.6 1.0 OD1 A:ASN82 4.6 21.7 1.0 CE1 A:PHE86 4.7 24.2 1.0 O A:GLN317 4.8 24.3 1.0 C A:ALA81 4.9 22.4 1.0 CA A:SER321 4.9 12.6 1.0 N A:ASN82 4.9 22.1 1.0 CB A:ASN82 4.9 22.1 1.0 CG A:ASN353 4.9 24.9 1.0

Y.Zhao, Y.Li. Dopamine Reuptake and Inhibitory Mechanisms in Human Dopamine Transporter Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07796-0