Chlorine in PDB 9drx: Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine

The binding sites of Chlorine atom in the Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine (pdb code 9drx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine, PDB code: 9drx:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl402 b:153.7 occ:1.00 CL01 D:IYJ402 0.0 153.7 1.0 C10 D:IYJ402 1.7 146.9 1.0 C08 D:IYJ402 2.7 144.7 1.0 C13 D:IYJ402 2.7 146.9 1.0 C09 D:IYJ402 3.0 146.3 1.0 CL02 D:IYJ402 3.1 153.4 1.0 N05 D:IYJ402 3.3 148.3 1.0 CE2 E:TYR58 3.3 98.9 1.0 C12 D:IYJ402 3.3 146.5 1.0 OH E:TYR58 3.8 105.4 1.0 N03 D:IYJ402 3.9 146.2 1.0 CZ E:TYR58 4.0 102.9 1.0 C15 D:IYJ402 4.0 146.2 1.0 C11 D:IYJ402 4.0 143.6 1.0 CE2 E:PHE77 4.1 80.2 1.0 CD2 E:TYR58 4.3 89.8 1.0 N04 D:IYJ402 4.4 145.5 1.0 C14 D:IYJ402 4.5 144.9 1.0 N06 D:IYJ402 4.8 146.1 1.0 ND2 E:ASN60 4.9 93.8 1.0 CD2 E:PHE77 4.9 75.9 1.0 C16 D:IYJ402 4.9 147.0 1.0 CG E:ASN60 5.0 89.9 1.0

Chlorine binding site 2 out of 2 in the Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Gabaa Receptor of BETA2-ALPHA1-BETA2-ALPHA1-GAMMA2 Subtype in Complex with Gaba Plus Lamotrigine within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl402 b:153.4 occ:1.00 CL02 D:IYJ402 0.0 153.4 1.0 C13 D:IYJ402 1.7 146.9 1.0 C15 D:IYJ402 2.7 146.2 1.0 C10 D:IYJ402 2.7 146.9 1.0 CL01 D:IYJ402 3.1 153.7 1.0 CG D:HIS102 3.3 87.6 1.0 CD2 D:HIS102 3.4 87.1 1.0 CB D:HIS102 3.5 83.8 1.0 ND1 D:HIS102 3.8 89.5 1.0 NE2 D:HIS102 4.0 86.1 1.0 C14 D:IYJ402 4.0 144.9 1.0 C08 D:IYJ402 4.0 144.7 1.0 CE1 D:HIS102 4.1 88.0 1.0 CA D:HIS102 4.2 86.4 1.0 CZ E:PHE77 4.3 73.9 1.0 CE2 E:PHE77 4.3 80.2 1.0 CZ D:PHE100 4.4 80.5 1.0 C11 D:IYJ402 4.5 143.6 1.0 O D:HIS102 4.6 98.2 1.0 CE2 D:PHE100 4.8 84.6 1.0 C D:HIS102 4.9 92.9 1.0

J.Zhou, C.M.Noviello, J.Teng, H.Moore, B.Lega, R.E.Hibbs. Resolving Native Gabaa Receptor Structures From the Human Brain Nature 2025.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-08454-1