Chlorine in PDB 9e4y: GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide

The binding sites of Chlorine atom in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide (pdb code 9e4y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide, PDB code: 9e4y:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1403 b:250.2 occ:1.00 CL A:CYZ1403 0.0 250.2 1.0 C13 A:CYZ1403 1.8 250.2 1.0 OG A:SER729 2.0 238.4 1.0 C14 A:CYZ1403 2.8 250.2 1.0 C12 A:CYZ1403 2.8 250.2 1.0 OD1 D:ASP760 3.1 262.9 1.0 S2 A:CYZ1403 3.2 250.2 1.0 O4 A:CYZ1403 3.3 250.2 1.0 CB A:SER729 3.3 238.4 1.0 N3 A:CYZ1403 3.4 250.2 1.0 N D:ASP760 3.8 262.9 1.0 CB D:ASP760 3.8 262.9 1.0 CG D:ASP760 3.8 262.9 1.0 CB D:LEU759 3.9 252.3 1.0 C11 A:CYZ1403 4.1 250.2 1.0 C10 A:CYZ1403 4.1 250.2 1.0 N A:SER729 4.2 238.4 1.0 CA A:SER729 4.3 238.4 1.0 CA D:ASP760 4.3 262.9 1.0 C D:LEU759 4.5 252.3 1.0 C9 A:CYZ1403 4.6 250.2 1.0 CD1 D:LEU759 4.7 252.3 1.0 CA D:LEU759 4.7 252.3 1.0 O3 A:CYZ1403 4.7 250.2 1.0 CG D:LEU759 4.9 252.3 1.0 O D:SER754 4.9 241.2 1.0 O D:PHE495 4.9 244.3 1.0 OD2 D:ASP760 5.0 262.9 1.0

Chlorine binding site 2 out of 4 in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1404 b:205.2 occ:1.00 CL A:CYZ1404 0.0 205.2 1.0 C13 A:CYZ1404 1.8 205.2 1.0 OG D:SER729 2.0 219.1 1.0 CB D:SER729 2.3 219.1 1.0 C14 A:CYZ1404 2.7 205.2 1.0 C12 A:CYZ1404 2.8 205.2 1.0 OD1 A:ASP760 3.0 197.3 1.0 N3 A:CYZ1404 3.1 205.2 1.0 S2 A:CYZ1404 3.1 205.2 1.0 O4 A:CYZ1404 3.2 205.2 1.0 CG A:ASP760 3.4 197.3 1.0 CA D:SER729 3.5 219.1 1.0 OD2 A:ASP760 3.5 197.3 1.0 N D:SER729 3.5 219.1 1.0 O A:PHE495 3.9 192.2 1.0 C10 A:CYZ1404 4.0 205.2 1.0 C11 A:CYZ1404 4.1 205.2 1.0 CB A:LEU759 4.3 191.4 1.0 N A:ASP760 4.4 197.3 1.0 CB A:ASP760 4.5 197.3 1.0 C D:SER729 4.6 219.1 1.0 O D:SER729 4.6 219.1 1.0 O3 A:CYZ1404 4.6 205.2 1.0 C9 A:CYZ1404 4.6 205.2 1.0 CA A:ASP760 4.7 197.3 1.0 C D:ASP728 4.7 238.8 1.0 CB A:MET496 4.8 197.7 1.0 C A:LEU759 4.8 191.4 1.0 C A:PHE495 4.9 192.2 1.0

Chlorine binding site 3 out of 4 in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1302 b:245.4 occ:1.00 CL B:CYZ1302 0.0 245.4 1.0 OG C:SER729 1.7 235.9 1.0 C13 B:CYZ1302 1.8 245.4 1.0 C14 B:CYZ1302 2.8 245.4 1.0 C12 B:CYZ1302 2.8 245.4 1.0 O4 B:CYZ1302 2.9 245.4 1.0 CB C:SER729 3.0 235.9 1.0 S2 B:CYZ1302 3.1 245.4 1.0 N3 B:CYZ1302 3.3 245.4 1.0 CB B:LEU759 3.5 260.4 1.0 N B:ASP760 3.8 265.5 1.0 C10 B:CYZ1302 4.1 245.4 1.0 C11 B:CYZ1302 4.1 245.4 1.0 O B:PHE495 4.2 239.5 1.0 CD1 B:LEU759 4.2 260.4 1.0 C B:LEU759 4.2 260.4 1.0 CA C:SER729 4.3 235.9 1.0 CB B:ASP760 4.3 265.5 1.0 OD1 B:ASP760 4.4 265.5 1.0 CB B:MET496 4.4 246.0 1.0 CA B:ASP760 4.4 265.5 1.0 CA B:LEU759 4.5 260.4 1.0 CG B:LEU759 4.5 260.4 1.0 N C:SER729 4.5 235.9 1.0 O3 B:CYZ1302 4.6 245.4 1.0 C9 B:CYZ1302 4.6 245.4 1.0 CG B:ASP760 4.9 265.5 1.0 O B:LEU759 5.0 260.4 1.0

Chlorine binding site 4 out of 4 in the GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of GLUA2-GAMMA2 Complex Bound to Memantine, Glutamate, and Cyclothiazide within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1302 b:212.7 occ:1.00 CL C:CYZ1302 0.0 212.7 1.0 C13 C:CYZ1302 1.8 212.7 1.0 OG B:SER729 2.0 224.0 1.0 CB B:SER729 2.3 224.0 1.0 C14 C:CYZ1302 2.7 212.7 1.0 C12 C:CYZ1302 2.9 212.7 1.0 OD1 C:ASP760 3.0 205.2 1.0 O4 C:CYZ1302 3.1 212.7 1.0 S2 C:CYZ1302 3.3 212.7 1.0 CG C:ASP760 3.4 205.2 1.0 OD2 C:ASP760 3.5 205.2 1.0 CA B:SER729 3.5 224.0 1.0 N B:SER729 3.6 224.0 1.0 N3 C:CYZ1302 3.7 212.7 1.0 O C:PHE495 4.0 198.2 1.0 C10 C:CYZ1302 4.0 212.7 1.0 CB C:LEU759 4.1 200.8 1.0 C11 C:CYZ1302 4.1 212.7 1.0 N C:ASP760 4.4 205.2 1.0 CB C:MET496 4.4 205.4 1.0 CD1 C:LEU759 4.5 200.8 1.0 CB C:ASP760 4.6 205.2 1.0 C B:SER729 4.6 224.0 1.0 C9 C:CYZ1302 4.6 212.7 1.0 C B:ASP728 4.7 246.7 1.0 O3 C:CYZ1302 4.7 212.7 1.0 CA C:MET496 4.8 205.4 1.0 CA C:ASP760 4.8 205.2 1.0 C C:LEU759 4.9 200.8 1.0 O B:SER729 5.0 224.0 1.0 CG C:LEU759 5.0 200.8 1.0

E.Carrillo, A.Montano Romero, C.U.Gonzalez, A.L.Turcu, S.Chen, H.Chen, H.Pan, S.Vazquez, E.C.Twomey, V.Jayarman. Memantine Inhibits Calcium-Permeable Ampa Receptors To Be Published.