Chlorine in PDB 9lvx: Di-Hexamer Form of Insulin Detemir at Ambient Temperature

The structure of Di-Hexamer Form of Insulin Detemir at Ambient Temperature, PDB code: 9lvx was solved by E.Ayan, I.Bahar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.32 / 2.70
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	80.898, 80.898, 80.414, 90, 90, 120
R / Rfree (%)	27.3 / 32.2

The structure of Di-Hexamer Form of Insulin Detemir at Ambient Temperature also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature (pdb code 9lvx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature, PDB code: 9lvx:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Di-Hexamer Form of Insulin Detemir at Ambient Temperature within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl103 b:26.9 occ:0.33 ZN B:ZN102 2.3 22.1 0.3 NE2 B:HIS10 3.7 23.8 1.0 CD1 B:LEU6 4.0 33.2 1.0 CB B:LEU6 4.0 30.2 1.0 CD2 B:HIS10 4.2 23.6 1.0 CG B:LEU6 4.5 30.4 1.0 CE1 B:HIS10 4.7 21.8 1.0 CD2 B:LEU6 5.0 27.1 1.0

Chlorine binding site 2 out of 4 in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Di-Hexamer Form of Insulin Detemir at Ambient Temperature within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl103 b:65.2 occ:0.33 ZN D:ZN102 2.5 32.5 0.3 O D:HOH204 3.3 73.0 0.7 CB D:LEU6 3.6 42.1 1.0 CD1 D:LEU6 3.6 45.7 1.0 NE2 D:HIS10 3.9 39.1 1.0 CG D:LEU6 4.2 40.1 1.0 CD2 D:HIS10 4.3 40.1 1.0 CA D:LEU6 4.8 39.7 1.0 CD2 D:LEU6 4.9 37.6 1.0 C D:LEU6 4.9 38.3 1.0 O D:LEU6 5.0 37.0 1.0

Chlorine binding site 3 out of 4 in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Di-Hexamer Form of Insulin Detemir at Ambient Temperature within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl103 b:23.0 occ:0.38 ZN F:ZN102 2.5 23.6 0.3 NE2 F:HIS10 3.7 25.7 1.0 CB F:LEU6 3.8 33.2 1.0 CD1 F:LEU6 3.9 34.4 1.0 CD2 F:HIS10 4.0 29.6 1.0 CG F:LEU6 4.4 33.3 1.0 O F:LEU6 4.7 34.4 1.0 C F:LEU6 4.8 34.3 1.0 CA F:LEU6 4.8 30.2 1.0 CE1 F:HIS10 4.9 34.4 1.0 CD2 F:LEU6 4.9 31.3 1.0

Chlorine binding site 4 out of 4 in the Di-Hexamer Form of Insulin Detemir at Ambient Temperature


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Di-Hexamer Form of Insulin Detemir at Ambient Temperature within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl103 b:25.9 occ:0.33 ZN H:ZN102 2.3 23.1 0.3 NE2 H:HIS10 3.7 30.9 1.0 CB H:LEU6 3.8 28.9 1.0 CD1 H:LEU6 4.1 30.2 1.0 CD2 H:HIS10 4.3 32.7 1.0 CG H:LEU6 4.5 28.8 1.0 O H:LEU6 4.7 33.4 1.0 CE1 H:HIS10 4.7 34.0 1.0 CA H:LEU6 4.9 32.9 1.0 C H:LEU6 4.9 33.7 1.0 CD2 H:LEU6 4.9 27.8 1.0

E.Ayan, I.Bahar. Di-Hexamer Form of Insulin Detemir at Ambient Temperature To Be Published.