Atomistry » Chlorine » PDB 1hba-1i3k » 1hpz
Atomistry »
  Chlorine »
    PDB 1hba-1i3k »
      1hpz »

Chlorine in PDB 1hpz: Human Immunodeficiency Virus Type 1

Enzymatic activity of Human Immunodeficiency Virus Type 1

All present enzymatic activity of Human Immunodeficiency Virus Type 1:
2.7.7.49;

Protein crystallography data

The structure of Human Immunodeficiency Virus Type 1, PDB code: 1hpz was solved by J.Ding, Y.Hsiou, E.Arnold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 3.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 223.100, 69.000, 104.000, 90.00, 106.80, 90.00
R / Rfree (%) 25.4 / 34.3

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Immunodeficiency Virus Type 1 (pdb code 1hpz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Immunodeficiency Virus Type 1, PDB code: 1hpz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 1hpz

Go back to Chlorine Binding Sites List in 1hpz
Chlorine binding site 1 out of 2 in the Human Immunodeficiency Virus Type 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Immunodeficiency Virus Type 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl561

b:33.2
occ:1.00
CL2 A:AAP561 0.0 33.2 1.0
C2 A:AAP561 1.9 41.5 1.0
O A:AAP561 2.7 66.8 1.0
C3 A:AAP561 2.8 46.2 1.0
C1 A:AAP561 2.9 49.6 1.0
CA A:AAP561 3.4 65.0 1.0
N' A:AAP561 3.4 70.9 1.0
C A:AAP561 3.4 67.2 1.0
O A:LYS101 3.9 76.0 1.0
O' A:AAP561 3.9 87.6 1.0
CD1 A:LEU100 3.9 63.1 1.0
C4 A:AAP561 4.1 52.5 1.0
CD2 A:LEU100 4.1 70.3 1.0
C6 A:AAP561 4.2 43.0 1.0
CB A:LEU100 4.2 70.2 1.0
CG1 A:VAL179 4.3 70.3 1.0
CG A:LEU100 4.3 66.0 1.0
C1' A:AAP561 4.5 75.8 1.0
ND2 A:ASN103 4.5 94.1 1.0
N A:LYS101 4.6 83.0 1.0
C5 A:AAP561 4.7 52.5 1.0
N A:AAP561 4.8 70.1 1.0
C' A:AAP561 4.8 86.6 1.0
CG A:ASN103 4.8 90.7 1.0
CB A:VAL179 4.9 61.6 1.0
C A:LYS101 4.9 80.3 1.0

Chlorine binding site 2 out of 2 in 1hpz

Go back to Chlorine Binding Sites List in 1hpz
Chlorine binding site 2 out of 2 in the Human Immunodeficiency Virus Type 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Immunodeficiency Virus Type 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl561

b:24.7
occ:1.00
CL6 A:AAP561 0.0 24.7 1.0
C6 A:AAP561 1.9 43.0 1.0
C5 A:AAP561 2.8 52.5 1.0
C1 A:AAP561 2.9 49.6 1.0
CD2 A:TYR188 3.0 64.5 1.0
CA A:AAP561 3.1 65.0 1.0
C6' A:AAP561 3.5 71.6 1.0
CG1 A:VAL106 3.8 50.4 1.0
CG A:TYR188 3.9 62.4 1.0
CB A:TYR188 3.9 51.4 1.0
CE2 A:TYR188 3.9 70.1 1.0
N' A:AAP561 4.1 70.9 1.0
CD1 A:LEU234 4.1 88.7 1.0
CD2 A:PHE227 4.2 56.3 1.0
C4 A:AAP561 4.2 52.5 1.0
C A:AAP561 4.2 67.2 1.0
C2 A:AAP561 4.2 41.5 1.0
C1' A:AAP561 4.3 75.8 1.0
CE2 A:PHE227 4.4 58.8 1.0
N A:AAP561 4.5 70.1 1.0
C5' A:AAP561 4.6 70.9 1.0
CM5 A:AAP561 4.6 69.5 1.0
CB A:LEU234 4.7 83.5 1.0
C3 A:AAP561 4.7 46.2 1.0
CB A:VAL106 4.8 57.6 1.0
CA A:TYR188 4.9 47.6 1.0
CG2 A:VAL108 4.9 37.8 1.0
CG A:LEU234 5.0 85.5 1.0
CG A:PHE227 5.0 57.1 1.0

Reference:

Y.Hsiou, J.Ding, K.Das, A.D.Clark Jr., P.L.Boyer, P.Lewi, P.A.Janssen, J.P.Kleim, M.Rosner, S.H.Hughes, E.Arnold. The LYS103ASN Mutation of Hiv-1 Rt: A Novel Mechanism of Drug Resistance. J.Mol.Biol. V. 309 437 2001.
ISSN: ISSN 0022-2836
PubMed: 11371163
DOI: 10.1006/JMBI.2001.4648
Page generated: Thu Jul 10 17:16:21 2025

Last articles

Mg in 6LT4
Mg in 6LY7
Mg in 6LY6
Mg in 6LY3
Mg in 6LX1
Mg in 6LTW
Mg in 6LVW
Mg in 6LUH
Mg in 6LTS
Mg in 6LTU
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy