Atomistry » Chlorine » PDB 1jfv-1k73 » 1jom
Atomistry »
  Chlorine »
    PDB 1jfv-1k73 »
      1jom »

Chlorine in PDB 1jom: The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase

Enzymatic activity of The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase

All present enzymatic activity of The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase:
1.5.1.3;

Protein crystallography data

The structure of The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase, PDB code: 1jom was solved by V.M.Reyes, H.Lee, J.Kraut, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 1.90
Space group P 65
Cell size a, b, c (Å), α, β, γ (°) 96.862, 96.862, 35.022, 90.00, 90.00, 120.00
R / Rfree (%) 14.2 / n/a

Other elements in 1jom:

The structure of The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase (pdb code 1jom). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase, PDB code: 1jom:

Chlorine binding site 1 out of 1 in 1jom

Go back to Chlorine Binding Sites List in 1jom
Chlorine binding site 1 out of 1 in the The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of the Binary Complex Between Folinic Acid (Leucovorin) and E. Coli Dihydrofolate Reductase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl163

b:8.3
occ:1.00
 O A:HOH257 3.1 13.7 1.0
N A:GLY96 3.2 9.5 1.0
OG1 A:THR46 3.2 7.7 1.0
O A:HOH391 3.3 37.0 1.0
N A:THR46 3.3 5.9 1.0
O A:HOH450 3.3 43.8 1.0
CA A:GLY43 3.6 4.2 1.0
C A:GLY43 3.6 8.7 1.0
N A:HIS45 3.6 3.5 1.0
CB A:HIS45 3.8 16.3 1.0
CB A:THR46 3.8 4.3 1.0
CA A:GLY96 3.8 9.6 1.0
O A:GLY43 3.9 7.9 1.0
CA A:HIS45 4.0 5.5 1.0
N A:GLY43 4.0 5.5 1.0
N A:ARG44 4.0 8.8 1.0
C A:HIS45 4.1 5.5 1.0
C A:GLY95 4.1 12.5 1.0
O A:GLY95 4.2 11.3 1.0
CA A:THR46 4.2 3.1 1.0
C A:ARG44 4.5 9.3 1.0
ND1 A:HIS45 4.6 42.7 1.0
CG A:HIS45 4.7 35.0 1.0
CA A:ARG44 4.8 6.4 1.0
C A:GLY96 4.8 7.0 1.0
O A:HOH301 4.8 24.4 1.0
O A:HOH296 4.9 17.3 1.0
CG2 A:VAL99 5.0 7.2 1.0

Reference:

H.Lee, V.M.Reyes, J.Kraut. Crystal Structures of Escherichia Coli Dihydrofolate Reductase Complexed with 5-Formyltetrahydrofolate (Folinic Acid) in Two Space Groups: Evidence For Enolization of Pteridine O4. Biochemistry V. 35 7012 1996.
ISSN: ISSN 0006-2960
PubMed: 8679526
DOI: 10.1021/BI960028G
Page generated: Fri Jul 19 23:04:28 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy