Atomistry » Chlorine » PDB 1nc7-1nvf » 1nhw
Atomistry »
  Chlorine »
    PDB 1nc7-1nvf »
      1nhw »

Chlorine in PDB 1nhw: Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase

Enzymatic activity of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase

All present enzymatic activity of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase:
1.3.1.9;

Protein crystallography data

The structure of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase, PDB code: 1nhw was solved by R.Perozzo, M.Kuo, A.S.Sidhu, J.T.Valiyaveettil, R.Bittman, W.R.Jacobs Jr., D.A.Fidock, J.C.Sacchettini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.35
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 133.365, 133.365, 83.862, 90.00, 90.00, 90.00
R / Rfree (%) 18.7 / 23.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase (pdb code 1nhw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase, PDB code: 1nhw:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 1nhw

Go back to Chlorine Binding Sites List in 1nhw
Chlorine binding site 1 out of 4 in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl600

b:76.5
occ:1.00
 CL2 A:TCC600 0.0 76.5 1.0
C11 A:TCC600 1.8 77.8 1.0
C12 A:TCC600 2.8 78.0 1.0
C10 A:TCC600 2.8 77.9 1.0
N A:ALA219 3.2 37.1 1.0
O A:ALA219 3.7 37.6 1.0
CA A:ASN218 3.8 37.6 1.0
C A:ASN218 3.9 37.3 1.0
CG1 A:VAL222 3.9 35.6 1.0
CA A:ALA219 4.0 37.4 1.0
C7 A:TCC600 4.1 78.0 1.0
CB A:ALA219 4.1 36.0 1.0
CB A:VAL222 4.1 36.4 1.0
C9 A:TCC600 4.1 77.9 1.0
C A:ALA219 4.3 38.1 1.0
CG2 A:VAL222 4.5 34.4 1.0
O A:ALA217 4.6 35.6 1.0
N A:ASN218 4.6 36.3 1.0
OD1 A:ASN218 4.6 42.7 1.0
C8 A:TCC600 4.7 78.1 1.0
CG A:ASN218 4.7 41.1 1.0
CB A:ASN218 4.9 39.8 1.0
C A:ALA217 4.9 34.5 1.0
O A:ASN218 5.0 38.7 1.0

Chlorine binding site 2 out of 4 in 1nhw

Go back to Chlorine Binding Sites List in 1nhw
Chlorine binding site 2 out of 4 in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl600

b:75.4
occ:1.00
 CL1 A:TCC600 0.0 75.4 1.0
C9 A:TCC600 1.8 77.9 1.0
C10 A:TCC600 2.8 77.9 1.0
C8 A:TCC600 2.8 78.1 1.0
N1 A:TCC600 3.1 78.0 1.0
CB A:ALA319 3.4 76.8 1.0
O5D A:NAD450 3.4 57.9 1.0
CB A:ALA217 3.5 29.2 1.0
O A:ALA217 3.6 35.6 1.0
C5B A:NAD450 3.8 59.5 1.0
O3 A:NAD450 3.8 59.9 1.0
C3D A:NAD450 3.8 54.9 1.0
O2N A:NAD450 3.9 57.6 1.0
C2D A:NAD450 4.0 54.7 1.0
C11 A:TCC600 4.1 77.8 1.0
PN A:NAD450 4.1 56.7 1.0
C A:ALA217 4.2 34.5 1.0
C7 A:TCC600 4.2 78.0 1.0
CA A:ALA217 4.2 31.8 1.0
N A:ALA217 4.2 30.8 1.0
O5B A:NAD450 4.3 61.3 1.0
C5D A:NAD450 4.4 56.4 1.0
O2A A:NAD450 4.4 59.6 1.0
O2D A:NAD450 4.4 55.8 1.0
C4 A:TCC600 4.5 78.0 1.0
PA A:NAD450 4.6 60.9 1.0
C12 A:TCC600 4.7 78.0 1.0
C4D A:NAD450 4.7 55.7 1.0
O3D A:NAD450 4.8 53.3 1.0
CA A:ALA319 4.8 77.4 1.0

Chlorine binding site 3 out of 4 in 1nhw

Go back to Chlorine Binding Sites List in 1nhw
Chlorine binding site 3 out of 4 in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl700

b:54.6
occ:1.00
 CL2 B:TCC700 0.0 54.6 1.0
C11 B:TCC700 1.7 55.0 1.0
C12 B:TCC700 2.7 55.9 1.0
C10 B:TCC700 2.8 55.9 1.0
N B:ALA219 2.9 24.2 1.0
O B:ALA219 3.4 24.6 1.0
C B:ASN218 3.6 24.4 1.0
CA B:ASN218 3.6 24.5 1.0
CB B:ALA219 3.7 18.8 1.0
CA B:ALA219 3.7 23.2 1.0
OD1 B:ASN218 3.7 32.0 1.0
C B:ALA219 3.9 24.6 1.0
C7 B:TCC700 4.1 55.5 1.0
CB B:VAL222 4.1 27.3 1.0
C9 B:TCC700 4.1 55.5 1.0
CG1 B:VAL222 4.3 28.8 1.0
N B:ASN218 4.4 22.6 1.0
CG2 B:VAL222 4.4 26.3 1.0
CG B:ASN218 4.6 30.6 1.0
O B:ASN218 4.6 26.2 1.0
C8 B:TCC700 4.6 55.9 1.0
O B:ALA217 4.7 19.9 1.0
CB B:ASN218 4.7 26.6 1.0
SD B:MET281 4.8 23.1 1.0
CG B:MET281 4.8 20.8 1.0
C B:ALA217 4.8 21.1 1.0

Chlorine binding site 4 out of 4 in 1nhw

Go back to Chlorine Binding Sites List in 1nhw
Chlorine binding site 4 out of 4 in the Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure Analysis of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl700

b:52.1
occ:1.00
 CL1 B:TCC700 0.0 52.1 1.0
C9 B:TCC700 1.8 55.5 1.0
C10 B:TCC700 2.8 55.9 1.0
C8 B:TCC700 2.8 55.9 1.0
N1 B:TCC700 3.0 56.0 1.0
CB B:ALA319 3.4 39.9 1.0
CB B:ALA217 3.5 17.5 1.0
O5D B:NAD550 3.5 24.6 1.0
O B:ALA217 3.5 19.9 1.0
C3D B:NAD550 3.8 25.9 1.0
C5B B:NAD550 3.8 29.4 1.0
O3 B:NAD550 3.9 31.3 1.0
C2D B:NAD550 4.0 24.5 1.0
C B:ALA217 4.1 21.1 1.0
N B:ALA217 4.1 19.4 1.0
CA B:ALA217 4.1 20.1 1.0
C11 B:TCC700 4.1 55.0 1.0
C7 B:TCC700 4.2 55.5 1.0
O2N B:NAD550 4.3 27.5 1.0
PN B:NAD550 4.3 28.5 1.0
O5B B:NAD550 4.4 31.5 1.0
C5D B:NAD550 4.4 23.7 1.0
O2A B:NAD550 4.4 29.8 1.0
O2D B:NAD550 4.4 26.3 1.0
C4 B:TCC700 4.5 57.0 1.0
PA B:NAD550 4.6 28.3 1.0
C12 B:TCC700 4.7 55.9 1.0
C4D B:NAD550 4.7 25.5 1.0
O3D B:NAD550 4.7 22.4 1.0
CA B:ALA319 4.8 41.1 1.0
C B:LEU216 4.9 18.8 1.0

Reference:

R.Perozzo, M.Kuo, A.S.Sidhu, J.T.Valiyaveettil, R.Bittman, W.R.Jacobs Jr., D.A.Fidock, J.C.Sacchettini. Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan For Malarial Enoyl Acyl Carrier Protein Reductase Year J.Biol.Chem. V. 277 13106 2002.
ISSN: ISSN 0021-9258
PubMed: 11792710
DOI: 10.1074/JBC.M112000200
Page generated: Thu Jul 10 18:27:38 2025

Last articles

Mg in 2UU7
Mg in 2UAG
Mg in 2UKD
Mg in 2SHK
Mg in 2TPS
Mg in 2TRT
Mg in 2TRA
Mg in 2RMK
Mg in 2RUS
Mg in 2TCT
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy