Chlorine in PDB 1ore: Human Adenine Phosphoribosyltransferase

All present enzymatic activity of Human Adenine Phosphoribosyltransferase:
2.4.2.7;

The structure of Human Adenine Phosphoribosyltransferase, PDB code: 1ore was solved by O.H.Thiemann, M.Silva, G.Oliva, C.H.T.P.Silva, J.Iulek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.10
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	58.309, 58.309, 109.535, 90.00, 90.00, 90.00
R / Rfree (%)	13.3 / 17.6

The binding sites of Chlorine atom in the Human Adenine Phosphoribosyltransferase (pdb code 1ore). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Adenine Phosphoribosyltransferase, PDB code: 1ore:

Chlorine binding site 1 out of 1 in the Human Adenine Phosphoribosyltransferase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Adenine Phosphoribosyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2001 b:18.6 occ:0.60 NH1 A:ARG87 0.5 21.5 0.4 CZ A:ARG87 1.3 23.2 0.4 NE A:ARG87 2.1 20.8 0.4 NH2 A:ARG87 2.3 25.0 0.4 NZ A:LYS91 2.7 23.4 1.0 CD A:ARG87 3.3 18.9 0.6 NH2 A:ARG87 3.4 21.3 0.6 CD A:ARG87 3.5 17.5 0.4 CD A:LYS91 3.6 23.8 1.0 CE A:LYS91 3.6 27.5 1.0 CB A:LYS91 3.9 18.6 1.0 CG A:LYS91 3.9 21.4 1.0 NE A:ARG87 4.0 22.0 0.6 CZ A:ARG87 4.1 22.7 0.6 CE2 A:PHE69 4.1 9.8 1.0 OD1 A:ASP65 4.3 10.3 1.0 CG A:ARG87 4.5 15.0 0.6 CG A:ARG87 4.5 14.5 0.4 CZ A:PHE69 4.6 8.8 1.0 CG A:ASP65 4.8 13.5 1.0 CB A:ARG87 4.9 11.6 0.6 OD2 A:ASP65 4.9 13.1 1.0 O A:HOH2150 5.0 16.7 1.0 CB A:ARG87 5.0 11.5 0.4

M.Silva, C.H.T.P.Silva, J.Iulek, O.H.Thiemann. Three-Dimensional Structure of Human Adenine Phosphoribosyltransferase and Its Relation to Dha-Urolithiasis. Biochemistry V. 43 7663 2004.
ISSN: ISSN 0006-2960
PubMed: 15196008
DOI: 10.1021/BI0360758