Atomistry » Chlorine » PDB 1qvf-1rkq » 1rf7
Atomistry »
  Chlorine »
    PDB 1qvf-1rkq »
      1rf7 »

Chlorine in PDB 1rf7: Structure of Dihydrofolate Reductase Complexed with Dihydrofolate

Enzymatic activity of Structure of Dihydrofolate Reductase Complexed with Dihydrofolate

All present enzymatic activity of Structure of Dihydrofolate Reductase Complexed with Dihydrofolate:
1.5.1.3;

Protein crystallography data

The structure of Structure of Dihydrofolate Reductase Complexed with Dihydrofolate, PDB code: 1rf7 was solved by M.R.Sawaya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 34.705, 38.917, 108.827, 90.00, 90.00, 90.00
R / Rfree (%) 17 / n/a

Other elements in 1rf7:

The structure of Structure of Dihydrofolate Reductase Complexed with Dihydrofolate also contains other interesting chemical elements:

Manganese (Mn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Dihydrofolate Reductase Complexed with Dihydrofolate (pdb code 1rf7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Dihydrofolate Reductase Complexed with Dihydrofolate, PDB code: 1rf7:

Chlorine binding site 1 out of 1 in 1rf7

Go back to Chlorine Binding Sites List in 1rf7
Chlorine binding site 1 out of 1 in the Structure of Dihydrofolate Reductase Complexed with Dihydrofolate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Dihydrofolate Reductase Complexed with Dihydrofolate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl299

b:16.8
occ:1.00
 N A:THR46 3.2 12.0 1.0
N A:GLY96 3.2 9.5 1.0
OG1 A:THR46 3.4 14.3 1.0
O A:HOH409 3.4 40.7 1.0
O A:HOH301 3.4 24.6 1.0
CA A:GLY43 3.5 10.0 1.0
C A:GLY43 3.6 11.1 1.0
N A:HIS45 3.6 15.2 1.0
CB A:HIS45 3.6 20.8 1.0
CA A:GLY96 3.8 7.7 1.0
O A:GLY43 3.8 12.2 1.0
CB A:THR46 3.9 13.5 1.0
CA A:HIS45 3.9 14.8 1.0
C A:HIS45 4.0 15.2 1.0
N A:GLY43 4.0 7.4 1.0
N A:ARG44 4.0 12.0 1.0
CA A:THR46 4.1 7.0 1.0
C A:GLY95 4.2 11.4 1.0
O A:GLY95 4.2 14.1 1.0
CD2 A:HIS45 4.3 71.7 1.0
CG A:HIS45 4.3 51.5 1.0
C A:ARG44 4.5 13.8 1.0
CE A:MET16 4.5 62.7 1.0
O A:HOH332 4.5 32.8 1.0
CG2 A:VAL99 4.8 13.8 1.0
CA A:ARG44 4.8 11.7 1.0
C A:GLY96 4.8 10.5 1.0
O A:HOH389 5.0 36.5 1.0

Reference:

M.R.Sawaya, J.Kraut. Loop and Subdomain Movements in the Mechanism of Escherichia Coli Dihydrofolate Reductase: Crystallographic Evidence. Biochemistry V. 36 586 1997.
ISSN: ISSN 0006-2960
PubMed: 9012674
DOI: 10.1021/BI962337C
Page generated: Sat Jul 20 01:54:04 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy