Atomistry » Chlorine » PDB 1ti7-1u33 » 1tnu
Atomistry »
  Chlorine »
    PDB 1ti7-1u33 »
      1tnu »

Chlorine in PDB 1tnu: Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob

Enzymatic activity of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob

All present enzymatic activity of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob:
2.5.1.59;

Protein crystallography data

The structure of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob, PDB code: 1tnu was solved by T.S.Reid, K.L.Terry, P.J.Casey, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.94 / 2.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 270.359, 266.551, 184.818, 90.00, 131.58, 90.00
R / Rfree (%) 19.3 / 21.2

Other elements in 1tnu:

The structure of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob also contains other interesting chemical elements:

Zinc (Zn) 6 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob (pdb code 1tnu). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob, PDB code: 1tnu:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 1tnu

Go back to Chlorine Binding Sites List in 1tnu
Chlorine binding site 1 out of 3 in the Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl379

b:59.9
occ:1.00
N D:GLN287 3.2 47.3 1.0
N D:PHE286 3.2 48.6 1.0
C D:LYS284 3.5 50.8 1.0
N D:ILE285 3.6 48.2 1.0
CG D:GLN287 3.7 51.9 1.0
CB D:GLN287 3.7 47.9 1.0
CB D:PHE286 3.8 43.9 1.0
CA D:PHE286 3.8 47.0 1.0
CA D:LYS284 3.8 52.2 1.0
NE2 D:GLN287 3.9 54.0 1.0
O D:LYS284 3.9 51.9 1.0
C D:ILE285 3.9 48.4 1.0
C D:PHE286 3.9 47.2 1.0
CA D:GLN287 4.0 49.0 1.0
CA D:ILE285 4.0 47.5 1.0
CD D:GLN287 4.1 55.1 1.0
CD D:LYS281 4.3 53.9 1.0
CA D:LYS281 4.5 49.5 1.0
O D:LYS281 4.5 47.2 1.0
O D:LEU280 4.6 51.6 1.0
N D:LYS284 4.8 53.0 1.0
CE D:LYS281 4.8 58.0 1.0
O D:ILE285 4.8 49.0 1.0
CB D:LYS284 4.9 53.3 1.0
CG D:PHE286 5.0 41.5 1.0
C D:LYS281 5.0 47.3 1.0

Chlorine binding site 2 out of 3 in 1tnu

Go back to Chlorine Binding Sites List in 1tnu
Chlorine binding site 2 out of 3 in the Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl379

b:55.2
occ:1.00
N F:PHE286 3.4 45.4 1.0
N F:GLN287 3.4 45.1 1.0
C F:LYS284 3.6 46.1 1.0
N F:ILE285 3.7 45.5 1.0
CG F:GLN287 3.8 47.8 1.0
CA F:LYS284 3.8 46.6 1.0
CB F:GLN287 3.8 46.2 1.0
NE2 F:GLN287 3.8 46.4 1.0
O F:LYS284 3.9 46.6 1.0
CB F:PHE286 3.9 45.6 1.0
CA F:PHE286 4.0 45.5 1.0
C F:ILE285 4.1 45.4 1.0
C F:PHE286 4.2 44.7 1.0
CA F:GLN287 4.2 46.1 1.0
CD F:GLN287 4.2 49.3 1.0
CA F:ILE285 4.2 44.8 1.0
CD F:LYS281 4.3 51.3 1.0
O F:LYS281 4.4 46.3 1.0
CA F:LYS281 4.5 46.0 1.0
CE F:LYS281 4.6 52.8 1.0
O F:LEU280 4.7 47.4 1.0
N F:LYS284 4.7 46.5 1.0
CB F:LYS284 4.8 48.6 1.0
CG F:LYS281 4.9 47.7 1.0
C F:LYS281 5.0 46.1 1.0

Chlorine binding site 3 out of 3 in 1tnu

Go back to Chlorine Binding Sites List in 1tnu
Chlorine binding site 3 out of 3 in the Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Rat Protein Geranylgeranyltransferase Type-I Complexed with A Ggpp Analog and A Gcincckvl Peptide Derived From Rhob within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Cl379

b:62.9
occ:1.00
N H:PHE286 3.2 53.5 1.0
N H:GLN287 3.3 54.0 1.0
C H:LYS284 3.5 55.3 1.0
N H:ILE285 3.6 54.2 1.0
CB H:PHE286 3.8 53.5 1.0
CA H:LYS284 3.8 55.8 1.0
CB H:GLN287 3.8 54.5 1.0
CG H:GLN287 3.8 58.3 1.0
CA H:PHE286 3.9 53.5 1.0
O H:LYS284 3.9 55.3 1.0
NE2 H:GLN287 3.9 60.4 1.0
C H:ILE285 4.0 52.9 1.0
C H:PHE286 4.0 52.9 1.0
CA H:ILE285 4.1 53.2 1.0
CA H:GLN287 4.1 54.8 1.0
CD H:LYS281 4.1 60.0 1.0
CD H:GLN287 4.2 60.2 1.0
CA H:LYS281 4.4 55.8 1.0
O H:LYS281 4.4 57.2 1.0
O H:LEU280 4.5 56.8 1.0
N H:LYS284 4.7 57.2 1.0
NZ H:LYS281 4.7 63.9 1.0
CE H:LYS281 4.8 62.6 1.0
CB H:LYS284 4.8 54.7 1.0
C H:LYS281 4.9 55.1 1.0
O H:ILE285 5.0 53.2 1.0

Reference:

T.S.Reid, K.L.Terry, P.J.Casey, L.S.Beese. Crystallographic Analysis of Caax Prenyltransferases Complexed with Substrates Defines Rules of Protein Substrate Selectivity. J.Mol.Biol. V. 343 417 2004.
ISSN: ISSN 0022-2836
PubMed: 15451670
DOI: 10.1016/J.JMB.2004.08.056
Page generated: Thu Jul 10 19:37:50 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy