Chlorine in PDB 1tvr: Hiv-1 Rt/9-Cl Tibo

All present enzymatic activity of Hiv-1 Rt/9-Cl Tibo:
2.7.7.49;

The structure of Hiv-1 Rt/9-Cl Tibo, PDB code: 1tvr was solved by K.Das, J.Ding, Y.Hsiou, E.Arnold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 3.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	226.000, 69.300, 104.100, 90.00, 107.00, 90.00
R / Rfree (%)	25.9 / n/a

The binding sites of Chlorine atom in the Hiv-1 Rt/9-Cl Tibo (pdb code 1tvr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hiv-1 Rt/9-Cl Tibo, PDB code: 1tvr:

Chlorine binding site 1 out of 1 in the Hiv-1 Rt/9-Cl Tibo


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hiv-1 Rt/9-Cl Tibo within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl600 b:45.0 occ:1.00 CL9 A:TB9600 0.0 45.0 1.0 C9 A:TB9600 1.8 45.0 1.0 C10 A:TB9600 2.7 45.0 1.0 C8 A:TB9600 2.8 45.0 1.0 OH A:TYR318 3.2 13.8 1.0 CB A:LEU234 3.3 40.1 1.0 O A:HIS235 3.4 43.8 1.0 N A:HIS235 3.7 44.3 1.0 C A:LEU234 3.7 43.0 1.0 C A:HIS235 3.7 45.2 1.0 CA A:LEU234 4.0 42.5 1.0 CE2 A:TYR318 4.0 13.2 1.0 CD2 A:PHE227 4.0 53.1 1.0 CZ A:TYR318 4.0 12.5 1.0 C1A A:TB9600 4.0 45.0 1.0 O A:LEU234 4.1 40.8 1.0 C7A A:TB9600 4.1 45.0 1.0 CA A:HIS235 4.2 45.6 1.0 N A:PRO236 4.3 45.2 1.0 CG A:LEU234 4.4 36.8 1.0 CD2 A:LEU234 4.5 33.3 1.0 CE2 A:PHE227 4.5 52.2 1.0 C3A A:TB9600 4.5 45.0 1.0 CA A:PRO236 4.7 45.2 1.0 CD1 A:LEU234 4.9 35.8 1.0

K.Das, J.Ding, Y.Hsiou, A.D.Clark Jr., H.Moereels, L.Koymans, K.Andries, R.Pauwels, P.A.Janssen, P.L.Boyer, P.Clark, R.H.Smith Jr., M.B.Kroeger Smith, C.J.Michejda, S.H.Hughes, E.Arnold. Crystal Structures of 8-Cl and 9-Cl Tibo Complexed with Wild-Type Hiv-1 Rt and 8-Cl Tibo Complexed with the TYR181CYS Hiv-1 Rt Drug-Resistant Mutant. J.Mol.Biol. V. 264 1085 1996.
ISSN: ISSN 0022-2836
PubMed: 9000632
DOI: 10.1006/JMBI.1996.0698