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Atomistry » Chlorine » PDB 1wvu-1xkk » 1x81 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 1wvu-1xkk » 1x81 » |
Chlorine in PDB 1x81: Farnesyl Transferase Structure of Jansen CompoundEnzymatic activity of Farnesyl Transferase Structure of Jansen Compound
All present enzymatic activity of Farnesyl Transferase Structure of Jansen Compound:
2.5.1.58; 2.5.1.59; Protein crystallography data
The structure of Farnesyl Transferase Structure of Jansen Compound, PDB code: 1x81
was solved by
Q.Li,
A.Claiborne,
T.Li,
L.Hasvold,
V.S.Stoll,
S.Muchmore,
C.G.Jakob,
W.Gu,
J.Cohen,
C.Hutchins,
D.Frost,
S.H.Rosenberg,
H.L.Sham,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1x81:
The structure of Farnesyl Transferase Structure of Jansen Compound also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Farnesyl Transferase Structure of Jansen Compound
(pdb code 1x81). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Farnesyl Transferase Structure of Jansen Compound, PDB code: 1x81: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 1x81Go back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Farnesyl Transferase Structure of Jansen Compound
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 1x81Go back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Farnesyl Transferase Structure of Jansen Compound
![]() Mono view ![]() Stereo pair view
Reference:
Q.Li,
A.Claiborne,
T.Li,
L.Hasvold,
V.S.Stoll,
S.Muchmore,
C.G.Jakob,
W.Gu,
J.Cohen,
C.Hutchins,
D.Frost,
S.H.Rosenberg,
H.L.Sham.
Design, Synthesis, and Activity of 4-Quinolone and Pyridone Compounds As Nonthiol-Containing Farnesyltransferase Inhibitors. Bioorg.Med.Chem.Lett. V. 14 5367 2004.
Page generated: Thu Jul 10 20:24:18 2025
ISSN: ISSN 0960-894X PubMed: 15454228 DOI: 10.1016/J.BMCL.2004.08.012 |
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