Chlorine in PDB 1yb5: Crystal Structure of Human Zeta-Crystallin with Bound Nadp

All present enzymatic activity of Crystal Structure of Human Zeta-Crystallin with Bound Nadp:
1.6.5.5;

The structure of Crystal Structure of Human Zeta-Crystallin with Bound Nadp, PDB code: 1yb5 was solved by J.Debreczeni, G.Berridge, K.Kavanagh, S.Colbrook, J.Bray, L.Williams, U.Oppermann, M.Sundstrom, C.Arrowsmith, A.Edwards, O.Gileadi, F.Vondelft, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	77.15 / 1.85
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	99.484, 110.239, 77.253, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 20.7

The binding sites of Chlorine atom in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp (pdb code 1yb5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp, PDB code: 1yb5:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Zeta-Crystallin with Bound Nadp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl816 b:31.0 occ:1.00 O1N A:NAP801 2.7 27.0 1.0 N A:GLY162 2.8 25.5 1.0 O A:GLY156 3.0 24.1 1.0 CA A:GLY159 3.2 25.9 1.0 C A:GLY159 3.2 26.3 1.0 N A:GLY159 3.3 25.2 1.0 CA A:GLY162 3.3 24.9 1.0 O5B A:NAP801 3.5 27.9 1.0 O A:GLY159 3.6 25.6 1.0 O3B A:NAP801 3.6 27.7 1.0 N A:GLY160 3.6 26.1 1.0 C4B A:NAP801 3.7 27.4 1.0 N A:VAL161 3.7 25.9 1.0 C A:VAL161 4.0 25.8 1.0 PN A:NAP801 4.0 28.1 1.0 C A:GLY156 4.0 24.5 1.0 C3B A:NAP801 4.2 26.8 1.0 C5B A:NAP801 4.2 27.0 1.0 CG A:MET224 4.2 27.4 1.0 CA A:VAL161 4.2 25.5 1.0 CE A:MET224 4.3 28.2 1.0 C A:GLY160 4.4 25.6 1.0 PA A:NAP801 4.4 26.2 1.0 O2A A:NAP801 4.4 26.4 1.0 CB A:VAL161 4.4 25.7 1.0 O3 A:NAP801 4.4 25.4 1.0 C A:ALA157 4.5 25.2 1.0 C A:SER158 4.5 25.4 1.0 C5D A:NAP801 4.5 28.4 1.0 CA A:GLY160 4.6 26.3 1.0 SD A:MET224 4.6 30.0 1.0 N A:SER158 4.6 25.4 1.0 C A:GLY162 4.6 25.6 1.0 O A:ALA157 4.7 25.6 1.0 O5D A:NAP801 4.8 28.4 1.0 CA A:ALA157 4.8 25.4 1.0 N A:ALA157 4.8 24.6 1.0 O4B A:NAP801 4.8 27.0 1.0 N A:LEU163 4.8 24.2 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Zeta-Crystallin with Bound Nadp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl818 b:34.5 occ:1.00 O A:HOH870 2.7 7.7 0.5 OG1 A:THR113 2.8 28.2 1.0 N A:ALA110 2.9 25.0 1.0 CA A:THR98 3.4 24.7 1.0 O A:SER97 3.5 23.2 1.0 C A:THR98 3.5 25.1 1.0 C A:SER97 3.5 24.9 1.0 CB A:SER97 3.6 26.9 1.0 CA A:ALA109 3.6 24.4 1.0 N A:THR98 3.6 23.9 1.0 CB A:ALA110 3.7 25.2 1.0 N A:ILE99 3.7 25.1 1.0 O A:HOH870 3.7 27.6 0.5 C A:ALA109 3.7 25.2 1.0 CG1 A:ILE99 3.8 24.6 1.0 CA A:ALA110 3.8 25.5 1.0 CB A:THR113 3.9 26.0 1.0 CB A:ALA109 3.9 24.5 1.0 CG2 A:THR113 4.0 25.9 1.0 O A:THR98 4.0 25.8 1.0 O A:ALA110 4.2 25.3 1.0 CA A:SER97 4.3 25.4 1.0 O A:HOH1078 4.5 35.8 1.0 CD1 A:ILE99 4.5 25.2 1.0 C A:ALA110 4.5 25.6 1.0 CA A:ILE99 4.6 25.1 1.0 O A:HOH1057 4.7 33.8 1.0 OG A:SER97 4.7 26.8 1.0 CB A:ILE99 4.8 25.0 1.0 CB A:THR98 4.9 24.4 1.0 N A:ALA109 4.9 23.9 1.0 O A:LEU108 4.9 24.2 1.0 O A:ALA109 5.0 24.6 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human Zeta-Crystallin with Bound Nadp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl817 b:32.8 occ:1.00 O1N B:NAP802 2.7 24.8 1.0 O B:GLY156 2.8 25.3 1.0 N B:GLY162 2.8 24.6 1.0 CA B:GLY159 3.2 25.2 1.0 N B:GLY159 3.2 24.9 1.0 C B:GLY159 3.2 24.9 1.0 CA B:GLY162 3.3 23.4 1.0 O5B B:NAP802 3.6 27.9 1.0 O B:GLY159 3.6 23.8 1.0 O3B B:NAP802 3.6 27.1 1.0 N B:GLY160 3.7 25.4 1.0 C4B B:NAP802 3.7 27.0 1.0 N B:VAL161 3.8 27.1 1.0 C B:GLY156 3.9 24.5 1.0 C B:VAL161 4.0 25.4 1.0 PN B:NAP802 4.1 26.8 1.0 C3B B:NAP802 4.2 27.5 1.0 C5B B:NAP802 4.2 25.6 1.0 CA B:VAL161 4.2 26.5 1.0 CG B:MET224 4.3 28.1 1.0 CE B:MET224 4.3 27.8 1.0 C B:GLY160 4.4 26.6 1.0 C B:ALA157 4.4 25.1 1.0 CB B:VAL161 4.4 26.8 1.0 N B:SER158 4.4 24.4 1.0 PA B:NAP802 4.5 27.2 1.0 C B:SER158 4.5 25.4 1.0 O3 B:NAP802 4.5 25.3 1.0 O2A B:NAP802 4.5 25.3 1.0 C5D B:NAP802 4.5 28.4 1.0 C B:GLY162 4.6 25.0 1.0 SD B:MET224 4.6 29.8 1.0 CA B:GLY160 4.6 26.3 1.0 N B:ALA157 4.6 24.5 1.0 CA B:ALA157 4.7 25.1 1.0 N B:LEU163 4.7 24.3 1.0 O B:ALA157 4.7 26.6 1.0 O5D B:NAP802 4.8 27.4 1.0 CA B:GLY156 4.9 25.2 1.0 O4B B:NAP802 4.9 25.4 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Human Zeta-Crystallin with Bound Nadp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Human Zeta-Crystallin with Bound Nadp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl819 b:27.2 occ:1.00 O B:HOH1155 2.6 37.3 1.0 O B:HOH864 2.9 16.8 1.0 O B:HOH924 3.0 31.7 1.0 CA B:PRO69 3.5 25.2 1.0 N B:GLY70 3.6 26.3 1.0 CG B:GLU51 3.6 27.3 1.0 CB B:PRO69 3.7 23.8 1.0 CE1 B:TYR67 3.9 24.5 1.0 CD1 B:ILE54 3.9 27.5 1.0 C B:PRO69 4.1 25.1 1.0 CG2 B:ILE54 4.1 22.6 1.0 CB B:GLU51 4.2 25.6 1.0 CA B:GLU51 4.2 25.1 1.0 CB B:ILE54 4.3 24.8 1.0 O B:HOH954 4.5 37.5 1.0 CD1 B:TYR67 4.6 25.4 1.0 CG1 B:ILE54 4.7 26.8 1.0 OH B:TYR67 4.7 24.4 1.0 CA B:GLY70 4.7 26.1 1.0 N B:PRO69 4.8 25.1 1.0 CZ B:TYR67 4.8 25.8 1.0 CG B:PRO69 4.8 24.3 1.0 O B:GLU51 4.8 22.7 1.0 O B:HOH841 4.8 19.9 1.0 CD B:GLU51 5.0 29.6 1.0

J.Debreczeni, G.Berridge, K.Kavanagh, S.Colbrook, J.Bray, L.Williams, U.Oppermann, M.Sundstrom, C.Arrowsmith, A.Edwards, O.Gileadi, F.Von Delft. Crystal Structure of Human Zeta-Crystallin at 1.85A To Be Published.