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Chlorine in PDB 1yvf: Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145
Enzymatic activity of Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145
All present enzymatic activity of Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145:
2.7.7.48;
2.7.7.48;
Protein crystallography data
The structure of Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145, PDB code: 1yvf
was solved by
J.A.Pfefferkorn,
M.L.Greene,
R.A.Nugent,
R.J.Gross,
M.A.Mitchell,
B.C.Finzel,
M.S.Harris,
P.A.Wells,
J.A.Shelly,
R.A.Anstadt,
R.E.Kilkuskie,
L.A.Kopta,
F.J.Schwende,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.00 / 2.50 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 90.879, 90.879, 188.516, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 24 / 30.3 |
Other elements in 1yvf:
The structure of Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145 also contains other interesting chemical elements:
| Bromine | (Br) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145
(pdb code 1yvf). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145, PDB code: 1yvf:
In total only one binding site of Chlorine was determined in the Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145, PDB code: 1yvf:
Chlorine binding site 1 out of 1 in 1yvf
Go back to
Chlorine Binding Sites List in 1yvf
Chlorine binding site 1 out
of 1 in the Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Hepatitis C Virus NS5B Rna-Dependent Rna Polymerase Complex with Inhibitor Pha-00729145 within 5.0Å range:
|
Reference:
J.A.Pfefferkorn,
M.L.Greene,
R.A.Nugent,
R.J.Gross,
M.A.Mitchell,
B.C.Finzel,
M.S.Harris,
P.A.Wells,
J.A.Shelly,
R.A.Anstadt,
R.E.Kilkuskie,
L.A.Kopta,
F.J.Schwende.
Inhibitors of Hcv NS5B Polymerase. Part 1: Evaluation of the Southern Region of (2Z)-2-(Benzoylamino)-3-(5-Phenyl-2-Furyl)Acrylic Acid. Bioorg.Med.Chem.Lett. V. 15 2481 2005.
ISSN: ISSN 0960-894X
PubMed: 15863301
DOI: 10.1016/J.BMCL.2005.03.066
Page generated: Thu Jul 10 20:46:26 2025
ISSN: ISSN 0960-894X
PubMed: 15863301
DOI: 10.1016/J.BMCL.2005.03.066
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