Chlorine in PDB 1zsx: Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2)

The structure of Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2), PDB code: 1zsx was solved by P.Wennerstrand, I.Johannsson, E.Ugochukwu, K.Kavanagh, A.Edwards, C.Arrowsmith, L.Williams, M.Sundstrom, K.Guo, F.Von Delft, U.Oppermann, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.30 / 1.90
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	113.231, 113.231, 142.505, 90.00, 90.00, 90.00
R / Rfree (%)	14.5 / 17.2

The binding sites of Chlorine atom in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) (pdb code 1zsx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2), PDB code: 1zsx:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl347 b:32.5 occ:1.00 O A:HOH824 3.1 28.0 1.0 O A:HOH899 3.3 48.3 1.0 N A:GLU202 3.3 23.4 1.0 NZ A:LYS210 3.4 43.9 1.0 CA A:ALA201 3.7 24.6 1.0 CB A:ALA201 4.0 22.8 1.0 CD A:LYS210 4.0 39.6 1.0 CA A:ARG175 4.0 25.7 1.0 C A:ALA201 4.0 24.5 1.0 CZ2 A:TRP229 4.0 29.5 1.0 CB A:GLU202 4.1 24.5 1.0 CG A:ARG175 4.3 37.2 1.0 CA A:GLU202 4.3 26.2 1.0 OE2 A:GLU199 4.3 39.9 1.0 CE A:LYS210 4.4 37.2 1.0 CB A:ARG175 4.4 26.8 1.0 CE2 A:TRP229 4.5 31.3 1.0 NE1 A:TRP229 4.5 29.0 1.0 N A:ARG175 4.5 24.2 1.0 O A:GLN200 4.6 27.0 1.0 O A:GLU202 4.9 27.3 1.0 CH2 A:TRP229 4.9 32.3 1.0 N A:ALA201 4.9 23.4 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl348 b:82.1 occ:1.00 SG A:CYS234 3.7 31.7 1.0 O A:ALA233 3.9 25.4 1.0 O A:HOH992 3.9 53.7 1.0 C A:ALA233 4.1 24.1 1.0 OE2 A:GLU202 4.2 37.4 1.0 CB A:CYS234 4.3 26.8 1.0 CD1 A:LEU259 4.4 28.2 1.0 CA A:ALA233 4.4 23.7 1.0 CB A:ALA233 4.5 25.1 1.0 O A:HOH844 4.5 53.3 1.0 CZ3 A:TRP258 4.7 36.9 1.0 CD1 A:ILE236 4.7 34.4 1.0 N A:CYS234 4.7 25.2 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl349 b:31.4 occ:0.25 ND2 A:ASN192 4.1 35.7 1.0 CB A:ASN192 4.6 30.7 1.0 O A:HOH813 4.7 44.2 1.0 CG A:ASN192 4.9 40.4 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl350 b:54.0 occ:1.00 OE2 A:GLU183 3.3 33.9 1.0 O A:HOH933 3.4 44.7 1.0 N A:MET152 3.4 22.6 1.0 CB A:MET152 4.0 23.9 1.0 OE1 A:GLU183 4.0 27.0 1.0 CD A:GLU183 4.1 30.3 1.0 O A:HOH805 4.1 23.5 1.0 CA A:PRO151 4.1 23.9 1.0 C A:PRO151 4.3 23.1 1.0 CA A:MET152 4.3 25.9 1.0 O A:THR150 4.8 24.8 1.0 CB A:PRO151 4.8 25.7 1.0 O A:HOH935 4.9 44.6 1.0

P.Wennerstrand, I.Johannsson, E.Ugochukwu, K.Kavanagh, A.Edwards, C.Arrowsmith, L.Williams, M.Sundstrom, K.Guo, F.Von Delft, U.Oppermann. Crystal Structure of Human Potassium Channel Kv Beta-Subunit (KCNAB2) To Be Published.